Nonalcoholic fatty liver disease and cardiovascular risk (literature review)


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Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in both Russia and the West. NAFLD is often associated with metabolic syndrome and can be considered as one of its components. Mortality of patients with NAFLD is resulting from not only progression of liver disease itself with the development of liver cirrhosis, liver failure or hepatocellular carcinoma, but also mortality from cardiovascular diseases (CVDs). This review presents data on the relationship of NAFLD and CVDs. Most studies suggest that NAFLD is associated with increased number of CVDs. The risk of CVDs increases with the progression of liver disease. NAFLD seems to be an independent factor contributing to the development and progression of cardiovascular diseases.

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About the authors

E. N Shirokova

FSBEI HE First MSMU n.a. I.M. Sechenov of RMH

MD, Prof. at the Department of Propaedeutics of Internal Diseases of the Medical Faculty

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