CURRENT POSSIBILITIES OF COMBINED THERAPY IN THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS


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Abstract

Combined therapy with inhibitors of sodium-glucose cotransporter 2nd type (SGLT-2) and metformin (additive effect on carbohydrate metabolism and complementary mechanism of action) provides a simultaneous effect on the multifactorial links of the pathogenesis of type 2 diabetes mellitus (DM2): safely reduces glycemia, reduces body weight and blood pressure that gives a high potential to this type of therapy. Sodium-glucose cotransporter type 2 inhibitors certainly play a positive role in the complex of therapeutic measures for the majority of DM2 patients and make this class of drugs a priority in modern appointments of diabetes specialists.

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About the authors

N. A Chemikova

FSBEIFPE «Russian Medical Academy of Continuous Postgraduate Education» of RMH

Email: nachendoc@yandex.ru
PhD, Associate Professor at the Department of Endocrinology Moscow

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