CLINICAL CASE OF TRANSTHYRETIN AMYLOIDOSIS WITH HEART, PLEVURE AND KIDNEY INVOLVEMENT


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详细

The article presents a case of systemic amyloidosis with heart (cardiomyopathy), pleura and kidney involvement in a 73-year-old female patient, in which the amyloid precursor protein was transthyretin, normally transporting thyroxine and retinol. The leading clinical manifestation of the disease was treatment-resistant hydrothorax. There is no information on the effective treatment of transthyretine amyloidosis in the literature. 8 months after the establishing diagnosis and 22 months after the appearance of the first clinical manifestations of the disease, the patient died from progressive cardiopulmonary insufficiency.

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作者简介

M. Ivanova

FSBEI HE “NWSMU n.a. I.I. Mechnikov" of RMH

Email: ivanovamariaig@mail.ru
PhD, Associate Professor at the Department of Faculty Therapy

S. Bolduyeva

FSBEI HE “NWSMU n.a. I.I. Mechnikov" of RMH

P. Ikonnikov

SPbSBHCI “City Multiprofile Hospital № 2"

参考

  1. Рамеев В.В., Козловская Л.В., Жданова Е.А., Гудкова К.В. Кардиоренальные взаимосвязи при системном амилоидозе. Тер. архив. 2013;6:51-9.
  2. Цветкова О.А., Варшавский В.А., Коган Е.А., Вартанова О.А., Абдуллаева. Г.Б. Случай первичного амилоидоза с преимущественным поражением сердца, легких и плевры. РМЖ. 2007;16: 1249-56.
  3. Серов В.В. Старческий амилоидоз: от тетрады Шварца до наших дней. РМЖ. 1997;20:8.

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