IMPULSIVE-COMPULSIVE DISORDERS IN PATIENTS WITH PARKINSON'S DISEASE ON THE BACKGROUND OF CHRONIC STIMULATION OF DEEP SUBCORTICAL STRUCTURES


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Abstract

The most effective drugs used in the treatment of Parkinson’s disease (PD), levodopa and dopamine receptor agonists, can lead to the development of impulsive-compulsive disorders (ICDs). Neurostimulation (NS) conducted to patients with complications of pharmacotherapy that are resistant to correction, has a dual effect on ICDs. On the one hand, the NS allows reducing the dose of prescribed dopaminergic drugs, which can reduce the severity of behavioral disorders in the postoperative period. On the other hand, there are several data on the increase or even occurrence of ICDs after surgery. This literature review considers various effects of the NS of subthalamic nucleus on ICDs in patients with PD.

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About the authors

S. M Omarova

FSBEI FPE RMACPE of RMH; Center for Extrapyramidal Diseases

Email: omarova_sm@mail.ru
postgraduate student at the Department of Neurology Moscow

N. V Fedorova

FSBEI FPE RMACPE of RMH; Center for Extrapyramidal Diseases

Moscow

E. V Bril

Federal Neurological Center FMBC n.a. A.I. Burnazyan of the FMBA of Russia

Moscow

A. A Tomskiy

Functional Neurosurgery Unit FSAI National Scientific and Practical Center for Neurosurgery n.a. Academician N. N. Burdenko of RMH

Moscow

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