EVALUATION OF INDICATORS OF ESOPHAGEAL PH-IMPEDANCEMETRY AND HIGH-RESOLUTION MANOMETRY IN PATIENTS WITH VARIOUS FORMS OF GASTROESOPHAGEAL REFLUX DISEASE AND BARRETT'S ESOPHAGUS


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Abstract

The article presents the results of a clinical study aimed at evaluation the regularity of changes in the basic parameters of esophageal pH-impedance and high-resolution manometry in patients with various forms of gastroesophageal reflux disease (non-erosive reflux disease, erosive reflux disease) and Barrett’s esophagus compared to healthy individuals. It was demonstrated that the more pronounced violations of esophageal motility, the more slow the acid clearance. In turn, delayed clearance and decrease of the lower esophageal sphincter tone lead to an increase in time with a pH <4 in the esophagus, which determines the severity of the acid refluxate effect on the mucous membrane.

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About the authors

E. V Barkalova

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Laboratory of Functional Methods of Examination in Gastroenterology Moscow

M. A Ovsepyan

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Laboratory of Functional Methods of Examination in Gastroenterology Moscow

D. N Andreyev

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Email: dna-mit8@mail.ru
PhD, Teaching Assistant at the Department of Propaedeutics of Internal Diseases and Gastroenterology, Researcher of the Laboratory of Functional Methods of Examination in Gastroenterology Moscow

Yu. A Kucheryavy

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Laboratory of Functional Methods of Examination in Gastroenterology Moscow

S. V Lyamina

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Laboratory of Functional Methods of Examination in Gastroenterology Moscow

I. V Mayev

FSBEI HE "MSMSU n.a. A.I. Evdokimov" of RMH

Laboratory of Functional Methods of Examination in Gastroenterology Moscow

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