HEREDITARY HEMOCHROMATOSIS (CASE REPORT)


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详细

The article presents 2 clinical cases of genetically confirmed hereditary hemochromatosis. The main criteria for diagnosis and treatment of this disease are given. In case of presence of cytolytic syndrome, it is necessary to include hemochromatosis in the diagnostic search. It is emphasized that timely and rational treatment of hemochromatosis can prevent the development of liver cirrhosis and significantly increase the life expectancy of patients.

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作者简介

N. Voloshina

Novosibirsk State Medical University

Email: navo@ngs.ru
MD, Prof. at the Department of Propaedeutics of Internal Diseases

Yu. Venzhina

Novosibirsk City Clinical Hospital №.12

N. Kazakova

Novosibirsk City Clinical Hospital №.12

I. Voloshina

Center of New Medical Technologies, Novosibirsk

参考

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  2. Adams P., Brissot P., Powell L.W. EASL International consensus conference on haemochromatosis. J. Hepatology 2000;33:487-96.
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  9. Phatak P., Brissot P., Wurster M., et al. A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis. Hepatology. 2010;52:1671.
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  11. Wood M.J., Powell L.W., Ramm G.A. Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood. 2008;111: 4456-462.

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