ACROMEGALY AND COMORBIDITY: DIAGNOSIS AND TREATMENT


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Abstract

Acromegaly is a severe chronic neuroendocrine disease, accompanied by such concomitant conditions as diabetes mellitus, cardiovascular, respiratory, and musculoskeletal disorders, and an increase in the number of neoplasms. Development of these conditions is associated with an increase in the growth hormone and insulin-like growth factor 1 levels. Therefore, the pathogenetic treatment of acromegaly, namely the use of somatostatin analogues, remains the main method of treatment and prevention of concomitant diseases. Nevertheless, in a number of cases, additional symptomatic treatment is necessary in persisting symptoms and controlled course of the disease.

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About the authors

M. B Antsiferov

Endocrinological Dispensary of the Moscow Healthcare Department

Moscow, Russia

L. I Astafyeva

SRI of Neurosurgery n.a. Acad. N.N. Burdenko

MD, Doctor at the Neurological Department Moscow, Russia

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