Differential diagnostics of lung injury in patients with systemic lupus erythematosus and antiphospholipidic syndrome: clinical observation


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Abstract

Background. In systemic lupus erythematosus (SLE), lung injury is not uncommon and requires therapy with cytostatics and glucocorticosteroids. With high clinical and immunological activity of SLE, an immunodeficiency state occurs, and the risk of infectious diseases, incl. tuberculosis, is increased. Description of the clinical case. A clinical case of a female patient with an interstitial lung injury is presented; differential diagnostics between tuberculous lesion and lung injury in SLE was performed. The importance of determination of the leading disease in connection with fundamentally different approaches to therapy for lupus pneumonitis and pulmonary tuberculosis is discussed. Conclusion. Lung injury in SLE in a patient with tuberculosis can cause diagnostic difficulties. Given the difference in tactics of treatment of SLE patients depending on the presence of comorbidities, immunosuppressive therapy in controversial situations should be prescribed with care.

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About the authors

E. A Belolipetskaya

North-Western State Medical University n.a. I.I. Mechnikov

Email: lisa_osutina@list.ru
Postgraduate Student at the Department of Therapy and Rheumatology

I. B Belyaeva

North-Western State Medical University n.a. I.I. Mechnikov

V. I Mazurov

North-Western State Medical University n.a. I.I. Mechnikov

O. V Inamova

Clinical Rheumatological Hospital № 25, St. Petersburg

M. S Petrova

Clinical Rheumatological Hospital № 25, St. Petersburg

E. A Mozharovskaya

Clinical Rheumatological Hospital № 25, St. Petersburg

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