The role of capsule endoscopy in the diagnosis of small intestine angiodysplasia


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Background. According to various studies, the cause of bleeding from the gastrointestinal tract in 3-27% of cases are angiodysplasias, abnormally dilated, convoluted blood vessels from 1 to 15 mm localized in the submucosal intestinal layer. There are a number of methods for diagnosing angiodysplasias, among which capsule endoscopy (CE) occupies an important place. Clinical guidelines recommend CE as a first-line procedure for patients with suspected small intestine bleeding the after performing EGDS and colonoscopy. Description of the clinical case. The article presents a rare clinical case of diagnosis and management of a patient with arteriovenous small intestine angiodysplasias. A 58-year-old patient for a long time presented various gastrointestinal complaints. During hospitalization, there were controversial bleeding symptoms. Comprehensive examination with CE revealed vascular injection, varicose veins, arteriovenous malformations without signs of bleeding at the time of the study at the border of the jejunum and ileum and in the ileum. The most likely reason for the decrease in hemoglobin level (up to 120 g/l) was bleeding from small intestine arteriovenous malformations. The patient received therapy with enzyme preparations, proton pump inhibitors, intestinal antiseptics, motility regulators with a positive effect in the form of relief of pain and dyspeptic syndromes, and normalization of stool. Conclusion. CE helps to diagnose acute and chronic bleeding, the sources of which are small intestine angiodysplasia; this allows to start timely treatment, as well as identify asymptomatic angiodysplasia, which makes it possible to prevent life-threatening complications.

Full Text

Restricted Access

About the authors

Anna O. Akopova

A.S. Loginov Moscow Clinical Research and Practical Center of the Moscow Healthcare Department

Email: anna.akopova@mail.ru
Junior Researcher at the Department of Diagnostics and General Therapy

A. I Parfenov

A.S. Loginov Moscow Clinical Research and Practical Center of the Moscow Healthcare Department

P. L Scherbakov

A.S. Loginov Moscow Clinical Research and Practical Center of the Moscow Healthcare Department

O. M Mikheeva

A.S. Loginov Moscow Clinical Research and Practical Center of the Moscow Healthcare Department

References

  1. Шелыгин Ю.А. Ачкасов С.И., Брехов Е.И. и др. Клинические рекомендации по диагностике и лечению взрослых больных ангиодисплазией кишечника. М., 2013. 13 с.
  2. Дубова Е.А., Щёголев А.И. Ангиодисплазия тонкой кишки. РЖГГК. 2007;2:84-88.
  3. Sami S.S., Al-Araji S.A., Ragunath K. Review article: gastrointestinal angiodysplasia - pathogenesis, diagnosis and management. Aliment Pharmacol Ther. 2014;39:15-34. doi: 10.1111/apt.12527.
  4. Pennazio M., Spada C., et al. Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatmentof small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE). Clinical Guideline. Endoscopy. 2015;47(4):352-76. doi: 10.1055/s-0034-1391855.
  5. Akin F.E., Yurekli O.T., Bolat A.D., et al. Analysis of nonsmall bowel lesions detected by capsule endoscopy in patients with potential small bowel bleeding. Diagn Ther Endosc. 2016;2016:9.063293E6. doi: 10.1155/2016/9063293.
  6. Gerson L.B., Fidler J.L., Cave D.R., Leighton J.A. ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding. Am J. Gastroenterol. 2015;1 10(9):1265-87. Doi: 10.1038/ ajg.2015.246.
  7. Holleran G., Hussey M., et al. Assessment of serum angiogenic factors as a diagnostic aid for small bowel angiodysplasia in patients with obscure gastrointestinal bleeding and anaemia.World J. Gastrointest.Pathophysiol. 2017;8(3):127-32. doi: 10.4291/wjgp.v8.i3.127.
  8. Zhang Z.-H., Qiu C.-H., Li Y. Different roles of capsule endoscopy and double-balloon enteroscopy in obscure small intestinal diseases. World J. Gastroenterol. 2015;21(23):72 9 7-304. doi: 10.3748/wjg.v21. І23.7297.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies