Poststroke rehabilitation: the processes of neuroplasticity and the possibility of increasing functional recovery. Results of open randomized control comparative study
- Authors: Ekusheva E.V.1,2
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Affiliations:
- Academy of Postgraduate Education, Federal Research and Clinical Center for Specialized Types of Health Care and Medical Technologies of FMBA of Russia
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 26, No 3 (2019)
- Pages: 57-64
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/297034
- DOI: https://doi.org/10.18565/pharmateca.2019.3.57-64
- ID: 297034
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Abstract
Background. Rehabilitation measures based on the neuroplasticity phenomenon are important for recovery of patients after ischemic stroke (IS), and the recovery rate after IS is primarily determined by functional activity and effective use of existing neuronal connections. Objective. Evaluation of the effect of Cytoflavin on the functional recovery rate when it is included in the complex therapy of patients in the early and late recovery periods of IS. Methods. The study include 60 patients with IS, randomized to 2 groups with or without the use of Cytoflavin as part of a comprehensive rehabilitation therapy for 35 days. Clinical and neurophysiological examination was carried out before and after the course of therapy. Results. The use of Cytoflavin in the complex therapy of patients after IS led to a significant reduction in neurological deficit, improvement of activity and patient independence, which was accompanied by a significant improvement in the functional activity of the efferent and afferent conduction systems (according to data obtained using neurophysiological examination methods) and contributed to an increase in plasticity of the whole system of voluntary motor activity, increasing the efficiency of further neurorehabilitation process and the likelihood of better recovery and a good outcome. Conclusion. The data obtained allow to recommend the use of Cytoflavin in addition to the background therapy of patients in the early and late recovery periods of IS.
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About the authors
Evgenia V. Ekusheva
Academy of Postgraduate Education, Federal Research and Clinical Center for Specialized Types of Health Care and Medical Technologies of FMBA of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: ekushevaev@mail.ru
MD, Professor, Head of the Department of Nervous Diseases at the Academy of Postgraduate Education
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