The effectiveness of omalizumab in severe atopic bronchial asthma in young patients: clinical cases from real practice


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Abstract

Patients with severe bronchial asthma (SBA) are refractory to traditional therapy; they have a high frequency of asthma exacerbations, unplanned visits to the doctor and seeking emergency medical care, hospitalizations. Currently, genetically engineering biological preparations have appeared for these patients, the first of which was omalizumab, a recombinant monoclonal antibody to immunoglobulin E. In the world and in our country, quite a lot of experience has been gained with the use of omalizumab in allergic SBA, but local clinical experience of using the drug is still of interest. This article is devoted to the experience of using omalizumab in two young patients with allergic SBA, who managed to get a pronounced improvement in lung function, as well as a significant improvement in the quality of life.

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About the authors

M. Yu Peredelskaya

Russian Medical Academy of Continuous Professional Education

Email: concy1984@gmail.com
Teaching Assistant, Department of Allergology and Immunology

N. M Nenasheva

Russian Medical Academy of Continuous Professional Education

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