Rare forms of chronic pancreatitis (literature review illustrated by clinical case)


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Abstract

Background. The article considers the problem of primary hyperparathyroidism (PHPT) as the cause of the development of chronic pancreatitis (CP). The most informative diagnostic methods for PHPT have been determined. The possibilities of examination and treatment of a patient with a rare form of CP are shown. Description of the clinical case. A clinical case of chronic calcifying pancreatitis in a patient with PHPT with symptoms of pancreatogenic diabetes mellitus and pancreatic hypertension is presented. The complexity of diagnosing this pathology and the possibility of collaborative management of the patient by specialists of various profiles: gastroenterologists, endocrinologists, radiologists and surgeons are shown. Conclusion. This clinical example demonstrates the difficulty of diagnosing PHPT in a patient with CP, whose successful treatment was ensured by the integrated coordinated work of gastroenterologists, endocrinologists and surgeons. It is emphasized that detection of hypercalcemia in patients with CP requires additional laboratory and instrumental tests, such as determining the parathyroid hormone level, parathyroid scintigraphy in combination with multispiral computed tomography. The resection of pathological parathyroid gland is the only method of treatment for PHPT, which allows to achieve normalization of biochemical parameters.

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About the authors

Karine A. Nikolskaya

A.S. Loginov Moscow Clinical Scientific Center

Email: k.nikolskaya@mknc.ru
Cand. Sci. (Med.), Senior Researchei at the Department of Pathology of the Pancreas and Biliary Tract Moscow, Russia

I. Yu Feydorov

A.S. Loginov Moscow Clinical Scientific Center

Moscow, Russia

E. A Dubtsova

A.S. Loginov Moscow Clinical Scientific Center

Moscow, Russia

M. V Chebotareva

A.S. Loginov Moscow Clinical Scientific Center

Moscow, Russia

D. S Bordin

A.S. Loginov Moscow Clinical Scientific Center; Tver State Medical University; A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Moscow, Russia; Tver, Russia

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