Sindrom defitsita vnimaniya i giperaktivnosti v sochetanii s tikoznymi rasstroystvami: podkhody k diagnostike i lecheniyu


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Attention deficit hyperactivity disorder (ADHD) is the most common cause of behavior problems and learning difficulties in pre-school and school age. Tic disorders is a common comorbid condition in ADHD and is found in 20-30% of patients. Among children with tic disorders, ADHD occurs in approximately 50-60% of cases. The incidence of a combination of tic disorders and ADHD seems to be higher than expected based on the incidence of these two diseases. The apparent association between tic disorders and ADHD has led to the assumption of common pathophysiological mechanisms of these diseases, consisting in changes in noradrenergic and dopaminergic synaptic transmission, which are accompanied by inadequate modulation of the cortico-striatal circuits with the resulting deficiency of inhibition of obsessive motives, sensory stimulation and motor response. The article discusses the features of clinical manifestations, the issues of diagnosis and treatment in cases of combinations of ADHD and tic disorders.

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作者简介

Nikolay Zavadenko

Pirogov Russian National Research Medical University

Email: zavadenko@mail.ru
Dr. Sci. (Med.), Professor, Head of the Department of Neurology, Neurosurgery and Medical Genetics n.a. Acad. L.O. Badalyan, Faculty of Pediatrics Moscow, Russia

N. Suvorinova

Pirogov Russian National Research Medical University

Department of Neurology, Neurosurgery and Medical Genetics n.a. Acad. L.O. Badalyan, Faculty of Pediatrics Moscow, Russia

A. Zavadenko

Pirogov Russian National Research Medical University

Department of Neurology, Neurosurgery and Medical Genetics n.a. Acad. L.O. Badalyan, Faculty of Pediatrics Moscow, Russia

Yu. Nesterovsky

Pirogov Russian National Research Medical University

Department of Neurology, Neurosurgery and Medical Genetics n.a. Acad. L.O. Badalyan, Faculty of Pediatrics Moscow, Russia

G. Khondkaryan

Pirogov Russian National Research Medical University

Department of Neurology, Neurosurgery and Medical Genetics n.a. Acad. L.O. Badalyan, Faculty of Pediatrics Moscow, Russia

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