Clinical case of mycosis fungoides
- Authors: Svechnikova E.V1, Marshani Z.B1
-
Affiliations:
- Outpatient Clinic № 1 of the Administrative Department of the President of the Russian Federation
- Issue: Vol 27, No 8 (2020)
- Pages: 106-109
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/312774
- DOI: https://doi.org/10.18565/pharmateca.2020.8.106-109
- ID: 312774
Cite item
Abstract
Background. The group of cutaneous T-cell lymphomas is a heterogeneous group of non-Hodgkin lymphomas, which are a malignant transformation of resident skin T-lymphocytes. Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphomas and accounts for almost 50% in their structure. This disease has a staged course and is characterized by the evolution of a rash - from spots to plaques and tumors. The course of the disease is quite indolent, and can last for years and even decades. Prior to diagnosis, patients usually have a history of nonspecific eczematous or psoriasiform dermatitis with nonspecific histological characteristics. Description of the clinical case. This article presents the clinical case of a patient with an established diagnosis of MF who has been followed-up by a dermatologist and allergologist for a long for toxicoderma. Conclusion. Thus, the role of related specialists in the diagnosis remains undeniably high, and the diagnosis of MF should be established on the basis of a comprehensive assessment of the clinical picture, histological and immunophenotypic studies.
Full Text
About the authors
E. V Svechnikova
Outpatient Clinic № 1 of the Administrative Department of the President of the Russian Federation
Email: elene-elene@bk.ru
Dr. Sci. (Med.), Head of the Department of Dermatovenerology and Cosmetology
Z. B Marshani
Outpatient Clinic № 1 of the Administrative Department of the President of the Russian Federation
References
- Чернова Н.Г., Коломейцев О.А. Современные возможности оптимизации лечения грибовидного микоза и синдрома Сезари. Клиническая онкогематология. Фундаментальные исследования и клиническая практика. 2018;1:34 41. [Chernova N.G., Kolomeytsev O.A. Modern possibilities for optimizing the treatment of fungal mycosis and Cesari syndrome. Klinicheskaya onkogematologiya. Fundamental'nye issledovaniya i klinicheskaya praktika. 2018;1:34-41. (in Russ.)]. doi: 10.21320/2500-2139-2018-11-134-41
- Филимонова Е.С., Дыхно Ю.А., Тарасенко С.Л. и др. Клинический случай грибовидного микоза. Сибирский онкологический журнал. 2014;6:64-8
- Демина О.М., Акилов О.Е., Румянцев О.Г Т-клеточные лимфомы кожи: современные данные патогенеза, клиники и терапии. Онкогематология. 2018;3:25-38. [Demina O.M., Akilov O.E., Rumyantsev O.G. T-cell lymphomas of the skin: current data on pathogenesis, clinical picture and therapy. Onkogematologia. 2018;3:25-38. (in Russ.)]. doi: 10.17650/1.818-8346-2018-13-3-25-38
- Bagherani N., Smoller B.R. An overview of cutaneous T cell lymphomas. F1000Res. 2016;5. doi: 10.12688/f1000research.8829.1
- Анпилогова Е.М. Т-клеточные лимфомы кожи: этиопатогенез, классификация, клиника. Российский журнал кожных и венерических болезней. 2015;3:42-7
- Krejsgaard T, Lindahl L.M., Mongan N.P, et al. Malignant inflammation in cutaneous T cell lymphoma - a hostile takeover. Semin Immunopathol. 2017;3:269-82. Doi: 10.1007/ s00281-016-0594-9
- Олисова О.Ю., Грабовская О.В., Тетушкина И.Н., Косоухова О.А. Т-клеточная лимфома кожи: трудности диагностики. Российский журнал кожных и венерических болезней. 2013;1:4-6