Combination of two hypoglycemic drugs for type 2 diabetes mellitus


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Abstract

Type 2 diabetes mellitus is a chronic progressive disease, which is based on a combination of several mechanisms leading to the development and progression of hyperglycemia. Over the past decades, new classes of hypoglycemic drugs have been used in clinical practice, affecting different links in the pathogenesis of the disease. The question of the possible earlier prescription of a combination of hypoglycemic drugs with different mechanisms of action is being discussed more and more often. This article discusses the advantages and disadvantages of different options for combined glucose-lowering therapy in patients with type 2 diabetes.

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About the authors

Tatyana B. Morgunova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: tanmorgun@mail.ru
Cand. Sci. (Med.) 8-2, Trubetskaya str., Moscow 119991, Russian Federation

V. V Fadeyev

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Moscow, Russia

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