Structure and risk factors for post-stroke apathy


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Resumo

Background. Apathy is one of the neuropsychiatric syndromes that complicate stroke. Objective. Evaluation of the clinical features and risk factors for post-stroke apathy (PSA). Methods. The study included 206 patients with new-onset cerebrovascular accident; the mean age of the patients was 66 ± 12 years. Neurological deficit was assessed, and apathy was diagnosed in accordance with the Starkstein criteria on the 1st, 7th, 14th days, 1st, 3rd, 6th and 12th months after the stroke. Results. The frequency of PSA was 24%. PSA was associated with older age, left-sided localization of the lesion, more severe neurological deficit and leukoaraiosis; patients with PSA were less adapted to everyday activities, more dependent on outside help. It was revealed that PSA was represented by two clinical variants: typical apathy and depressive apathy. Different types of apathy were associated with a number of risk factors in different ways: depressive apathy was more common in older patients, women; typical apathy occurred more often in men. Conclusion. The data obtained indicate the advisability of further study of mental disorders, incl. PSA, in stroke patients. This will help open up new possibilities for a more differentiated therapy of post-stroke affective disorders, and can significantly improve the quality of life of stroke patients.

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Sobre autores

Elizaveta Petrova

Pirogov Medical University

Email: 6332011@mail.ru
Dr. Sci. (Med.), Professor at the Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine Moscow, Russia

E. Ponevezhskaya

Pirogov Medical University

Moscow, Russia

M. Savina

Mental Health Research Center

Moscow, Russia

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