The effect of hormonal therapy for endometriosis on the course of migraine. Description of the clinical case


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Abstract

Background. Migraine and endometriosis are comorbid diseases. Treatment of endometriosis often involves long-term hormonal therapy and can worsen the course of migraine, which is widespread among this category of patients. Description of the clinical case. The article presents a clinical case of undiagnosed migraine, which led to a worsening of the course of headache in a patient with advanced genital endometriosis during therapy with combined oral contraceptives (COCs). The diagnostic criteria for migraine were discussed; effective therapy with sumatriptan for severe menstrual attacks was prescribed; comparative analysis of hormonal types of therapy for endometriosis and successful treatment due to the replacement of COCs with monotherapy with dienogest were carried out. Conclusion. Due to the high comorbidity of migraine and endometriosis, it is necessary to purposefully diagnose migraine and to select hormonal therapy taking into account contraindications and its possible effect on the course of headache.

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About the authors

U. A Bagirova

Sechenov University

Department of Nervous Diseases IPGE Russia, Moscow

Elena G. Filatova

Sechenov University

Email: eg-filatova@mail.ru
Dr. Sci. (Med.), Professor at the Department of Nervous Diseases IPGE Russia, Moscow

G. E Chernukha

National Medical Research Center for Obstetrics, Gynecology and Perinatology n.a. Academician V.I. Kulakov

Russia, Moscow

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