Influence of impaired regulation of carbohydrate metabolism on circadian glycemic variability and its role in the development of cardiovascular complications in patients with type 2 diabetes mellitus


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Abstract

The circadian system serves as one of the most fundamental properties of the body: it generates circadian rhythms of behavioral and physiological reactions, allows to predict and adapt to daily changing environmental conditions, and is the main regulator of all types of metabolic processes, including carbohydrate metabolism. Violations of its functioning at any stage lead to a failure of the diurnal rhythm of glucose dynamics, increase its variability and rightfully occupy an independent place among the pathogenetic factors involved in the formation of complications in patients with type 2 diabetes mellitus.

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About the authors

Tatiana A. Ilyinskaya

S.M. Kirov Military Medical Academy

Email: tany120982@mail.ru
Cand. Sci.(Med.), Lecturer at the 1st Department of Therapy (for postgraduate education) 6 Academician Lebedev St., St. Petersburg 194044, Russian Federation

V. P Kitsyshin

S.M. Kirov Military Medical Academy

St. Petersburg, Russia

V. V Salukhov

S.M. Kirov Military Medical Academy

St. Petersburg, Russia

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