Management of a coughing patient


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The article deals with the problem of management of a coughing patient. A large number of causes (various conditions and forms) of cough are known, therefore, special attention is paid to the need for a detailed study of the cough characteristics, which enables deliberate approach to the therapy. The algorithm for management of a coughing patient helps to decide on pharmacological - etiotropic, symptomatic - therapy or non-pharmacological treatment. Information is provided on the effective treatment of cough using a fixed combination of medications - bromhexine+guaifenesin+salbutamol (Ascoril expectorant).

Full Text

Restricted Access

About the authors

Irina L. Klyachkina

Russian Medical Academy of Continuous Professional Education

Email: formozailk2012@yandex.ru
Cand. Sci. (Med.), Associate Professor at the Department of Pulmonology Moscow, Russia

References

  1. Morice A.H., Mihqvist E., Bieksiene K., et al. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020;55:1901136. doi: 10.1183/13993003.01136-2019.
  2. Чучалин А.Е, Абросимов В.Н. Кашель. 2-е изд., перераб. и допол. М., 2012. 128 с.
  3. Шварц Л. С. Кашель. Большая Медицинская Энциклопедия. 2-е изд. Том 12, столбцы 539-514. М., 1959
  4. Brooks S.M. Perspective on the human cough reflex. Cough. 2011;7:10. doi: 10.1186/17459974-7-10.
  5. Morice A.H. Epidemiology of cough. Pulm Pharmacol Ther. 2002;15(3):253-59. doi: 10.1006/pupt.2002.0352.
  6. Irwin R.S., et al. Managing cough as a defense mechanism and as a symptom. A consensus panel report of the ACCP Chest. 1998;2:133S-181S. doi: 10.1378/chest.114.2_supplement.133s.
  7. O'Connell F., Thomas V.E., Studham J.M., et al. Capsaicin cough sensitivity increases during upper respiratory infection. Respir Med. 1996;90:279-286. doi: 10.1016/s0954-6111(96)90099-2.
  8. Dicpinigaitis P.V., Bhat R., Rhoton W.A., et al. Effect of viral upper respiratory tract infection on the urge-to-cough sensation. Respir Med. 2011;105:615-18. Doi: 10.1016/j. rmed.2010.12.002.
  9. Morice A.H., Millqvist E., Belvisi M.G., et al. Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J. 2014;44:1132-doi: 10.1183/09031936.00218613.
  10. Клячкина И.Л. Кашель у женщин. Фарматека. 2019;5:127-132
  11. Синопальников А.И., Клячкина И.Л. Кашель: дифференциальная диагностика и дифференцированное лечение. Терапевтический архив. 2012;8:95-102
  12. Irwin R.S., Madison J.M. The diagnosis and treatment of cough. N Engl J Med. 2000;343:1715-21. Doi: 10.1056/ NEJM200012073432308.
  13. Moris A.H., Kastelik J.A. Cough 1: Chronic cough in adults. Review series. Thorax. 2003;58:901-7. doi: 10.1136/thorax.58.10.901.
  14. Irwin R.S., French C.L., Chang A.B., Altman K.W. Classification of Cough as a Symptom in Adults and Management Algorithms. CHEST Guideline and Expert Panel Report. Chest. 2018;153(1):196-209. doi: 10.1016/j.chest.2017.10.016.
  15. Morice A.H. Cough and sputum. In: ERS Handbook Respiratory Medicine. Editors Palange P., Simonds A. UK: Latimer Trend&Co. Ltd, 2010, P 23-29, 54.
  16. Eccles R., Fietze I., Rose U-W. Rationale for Treatment of Common Cold and Flu with Multi-Ingredient Combination Products for Multi-Symptom Relief in Adults. Open J Respir Dis. 2014;24:73-8.
  17. Kardos R Management of cough in adults. Breathe. 2010;2:123-133.
  18. Вотчал Б.Е. Очерки клинической фармакологии. М.,1965. С. 428-33. [Votchal B.E. Essays on Clinical Pharmacology. M., 1965. R 428-33. (In Russ.)].
  19. Dicpinigaitis R.V., Morice A.H., Birring S.S., et al. Antitussive Drugs - Rast, Present, and Future. Pharmacol Rev. 2014;66(2):468-512. doi: 10.1124/pr.111.005116.
  20. Rogers D.F. Mucoactive agents for airway mucus hypersecretory diseases. Respir Care. 2007;52(9):1176-93.
  21. Balsamo R., Lanata L., Egan C.G. Mucoactive drugs. Eur Respir Rev. 2010;19(116):127-33. doi: 10.1183/09059180.00003510.
  22. Клячкина И.Л., Синопальников А.И. Мукоактивные препараты. В кн.: Рациональная фармакотерапия заболеваний органов дыхания. Под ред. Чучалина А.Г Руководство для практикующих врачей. 2-е изд., исправ. и допол. М., 2013. С. 103-17
  23. Chung K.F., Canning B., McGarvey L. Eight International London Cough Symposium 2014: Cough hypersensitivity syndrome as the basis for chronic cough. Pulm Pharmacol Ther. 2015;35:76-80. Doi: 10.1016/j. pupt.2015.08.009.
  24. Mazzone S.B., Chung K.F., McGarvey L. The heterogeneity of chronic cough: a case for endotypes of cough hypersensitivity. Lancet Respir Med. 2018;6:636-46. doi: 10.1016/S2213-2600(18)30150-4.
  25. Dicpinigaitis P.V., Gayle Y.E. Effect of Guaifenesin on Cough Reflex Sensitivity. CHEST 2003;124:2178-2181. doi: 10.1378/ chest.124.6.2178.
  26. Morice A.H., Kantar A., Dicpinigaitis P.V., et al. Treating acute cough: wet versus dry - have we got the paradigm wrong? ERJ Open Res. 2015;1(2):00055-2015. doi: 10.1183/23120541.00055-2015.
  27. Jayaram S., Desai A. Efficacy, and safety of Ascoril expectorant and other cough formula in the treatment of cough management in paediatric and adult patients - a randomised doubleblind comparative trial. J Indian Med Assoc. 2000;98:68-70.
  28. Ainapure S.S., Desai A., Korde K. Efficacy and safety of Ascoril in the management of cough -National Study Group report. J Indian Med Assoc. 2001;99:111, 114.
  29. Федосеев Г.Б., Орлова Н.Ю., Шалюга Л.В. Применение препарата «АСКОРИЛ» в амбулаторной практике. Новые Санкт-Петербургские врачебные ведомости. 2002;1(19): 69-70.
  30. Федосеев Г.Б., Зинакова М.К., Ровкина Е.И., Щукина Т.В. Клинические аспекты применении аскорила в пульмонологической клинике. Новые Санкт-Петербургские врачебные ведомости. 2002;2(20):64-67
  31. Корж А.Н., Краснокутский С.В., Васькив Н.Н. Применение препарата «Аскорил» в лечении больных хроническим обструктивным заболеванием легких. Consilium medicum Ukraina. 2007;1(4):15-17
  32. Клячкина И.Л. Лечение кашля при острых респираторных вирусных инфекциях у пациентов группы риска. ВМЖ. 2009;7:40-45
  33. Клячкина И.Л., Дмитриев Ю.К. Лечение нетяжелых обострений хрнонической обструктивной болезни легких. Клиническая медицина. 2012;3:69-73
  34. Prabhu Shankar S., Chandrashekharan S., Bolmall C.S., Baliga V. Efficacy, safety and tolerability of salbutamol+guaiphenesin+bromh exine (Ascoril) expectorant versus expectorants containing salbutamol and either guaiphenesin or bromhexine in productive cough: a randomised controlled comparative study. J Indian Med Assoc. 2010;108:313-14, 316-18, 320
  35. Григорьева Н.Ю. Оценка клинической эффективности и безопасности комбинированного препарата Аскорил у больных c коморбидной бронхолегочной и сердечно-сосудистой патологией. Русский медицинский журнал. 2013;29:1475-79
  36. Клячкина И.Л. Хронический бронхит: фармакотерапевтический фокус на гиперсенситивный компонент кашля. Consilium Medicum. 2020;22(3):46-54

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2021 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies