Ways to increase the endometrium receptivity in cryotransfers


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Abstract

Cryotransfer allows to choose the most favorable time for implantation, as well as to determine the most viable embryo. Two-thirds of implantation failures are due to a violation of the interaction of the embryo and the endometrium. Currently, a range of methods has been developed that increase the endometrium receptivity and increase the chance of pregnancy after cryotransfer. Thee include immunotherapy, endometrial scratching, ERA test, uterine artery vasodilation, instillation of human chorionic gonadotropin. The use of somatotropin, platelet-rich plasma, metformin, acupuncture and determination of the microflora of the endometrium is also discussed. Modern research is aimed at understanding the mechanisms affecting the endometrium to prevent defective embryo implantation, as well as to increase receptivity by artificial methods and to determine the ideal moment and microenvironment of the endometrium for cryotransfer.

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About the authors

L. A Dontsova

LLC “Center ECO"

Email: ldontsova1987@mail.ru
Obstetrician-Gynecologist, Reproductologist, Chief Physician Volgograd, Russia

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