Medication errors as risk factor for drug-induced diseases


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Medications errors (ME) can significantly worsen patient’s prognosis, heavy harm to health, increase mortality rates, and be a prominent risk factor for the development of drug-induced diseases. Approximately one third of adverse drug reactions are associated with ME during drug therapy. ME may occur at different levels of the pharmacotherapy involving prescribing, transcribing, dispensing, administering, monitoring as well as during medication production, storage, and preparation for use. Studies suggests that ME associated with certain factors such as information relating to the history of the patient’s disease; medications themselves; communication between heath care specialists in order to transfer information about dug; drug classification, naming and labeling; storage, preservation and standardization of drugs; attainment, using and monitoring devices for receiving drugs; environmental factors; competence and education of medical personnel and patient; monitoring of the safety profile and risks of pharmacotherapy. Due to the exceptional importance of ME in the development of drug-induced adverse condition and complication, various interventions to prevent and minimize such errors are being developed and tested in practice. These approaches include pharmacist-led medication reconciliation, computerized medication reconciliation, computerized physician order entry with or without clinical decision support system, partnership cooperation with pharmacists and interdisciplinary collaboration, training of doctors and patients, involving trained medication experts, an automated drug distribution system, the use of electronic administration system and methods for facilitating distribution of drugs to patients. Based on the analysis of available literature, it can be concluded that further active research and practical work is needed to minimize the prevalence of ME in view of their principal role in the aspects of the pharmacotherapy safety.

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作者简介

D. Sychev

Medical Academy of Continuous Professional Education

Moscow, Russia

Olga Ostroumova

Medical Academy of Continuous Professional Education; I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: ostroumova.olga@mail.ru
Dr. Sci. (Med.), Professor, Head of the Therapy and Polymorbid Pathology Department n.a. Academician M.S. Vovsi, Russian Medical Academy of Continuous Professional Education; Professor of the Department of Clinical Pharmacology and Propedeutics of Internal Diseases, I.M. Sechenov First Moscow State Medical University (Sechenov University) Moscow, Russia

A. Kochetkov

Medical Academy of Continuous Professional Education

Moscow, Russia

A. Pereverzev

Medical Academy of Continuous Professional Education

Moscow, Russia

T. Ostroumova

Medical Academy of Continuous Professional Education; I.M. Sechenov First Moscow State Medical University (Sechenov University)

Moscow, Russia

M. Klepikova

Medical Academy of Continuous Professional Education

Moscow, Russia

E. Ebzeeva

Medical Academy of Continuous Professional Education

Moscow, Russia

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