New potentials for the correction of non-neoplastic melanin hyperpigmentation
- Authors: Kruglova L.S.1, Avagumyan M.A2
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Affiliations:
- Central State Medical Academy of Department of Presidential Affairs
- Medical Research and Education Center of the Lomonosov Moscow State University (University Clinic)
- Issue: Vol 28, No 14 (2021)
- Pages: 63-69
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/313339
- DOI: https://doi.org/10.18565/pharmateca.2021.14.63-69
- ID: 313339
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Abstract
Background. Hyperpigmentation is one of the most common reasons for seeking medical attention in aesthetic medicine. The main reasons for the formation of hyperpigmentation include primarily genetic, endocrine factors, and ultraviolet radiation, or their combination. Hyperpigmentation refers to aesthetic defects and can significantly reduce the quality of life of patients, especially when localized in open areas, which makes it relevant to study the effectiveness of new methods of therapy. Methods. The study included 36 patients with melasma, or post-inflammatory hyperpigmentation (PIH). All patients used Eucerin AntiPigment dermatocosmetics for 12 weeks. Efficacy was assessed using mexametry, IGA (Investigator’s Global Assessment) and DLQI (Dermatology Life Quality Index) clinical indices. Results. According to mexametry, all patients showed positive dynamics. The mexametry index decreased on average by 91.2% in patients with melasma and by 89.8% with PIH. The mean IGA and DLQI scores in patients with melasma decreased by 91.2 and 77.2% and in patients with PIH - by 89.8 and 74.3%. Conclusions. The use of Eucerin Anti-Pigment dermatocosmetics is effective in reducing hyperpigmentation and preventing its reappearance. Improvement is noted already after 2 weeks of use with further continuous improvement. The use of Eucerin Anti-Pigment is highly safe and well tolerated.
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About the authors
Larisa S. Kruglova
Central State Medical Academy of Department of Presidential Affairs
Email: kruglovals@mail.ru
Dr. Sci (Med.), Professor, Vice-Rector for Academic Affairs, Head of the Department of Dermatovenereology and Cosmetology
M. A Avagumyan
Medical Research and Education Center of the Lomonosov Moscow State University (University Clinic)
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