Miescher’s granulomatous cheilitis or delayed inflammatory edema of the upper lip after filler injection: difficulties in differential diagnosis


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Abstract

Background. Granulomatous cheilitis (GC) is a chronic granulomatous inflammation of the lips (usually the upper one), accompanied by non-pitting diffuse painless edema. This disease can occur in the form of a monosymptomatic form (Miescher’s syndrome) or be part of the Melkersson-Rosenthal syndrome triad (granulomatous cheilitis, facial paralysis, folded tongue). The disease is rare, and the etiology remains unknown. Description of the clinical case. This article presents a clinical case of GC in a 50-year-old female patient, who was followed up by a beautician for a long time with a presumptive diagnosis of delayed inflammatory edema of the upper lip after filler injection. Conclusion. This clinical case is of interest to doctors of various specialties due to the need for interdisciplinary interaction for the timely diagnosis, observation and treatment of such patients.

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About the authors

Evgeniya V. Ikonnikova

Central State Medical Academy of Department of Presidential Affairs; Institute of Plastic Surgery and Cosmetology

Email: evikonnikova@bk.ru
Associate Professor at the Department of Dermatovenereology and Cosmetology

L. S Kruglova

Central State Medical Academy of Department of Presidential Affairs; Institute of Plastic Surgery and Cosmetology

N. E Manturova

Institute of Plastic Surgery and Cosmetology; Pirogov Russian National Research Medical University

V. A Shchekochikhin

Central State Medical Academy of Department of Presidential Affairs

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