Features of the clinical course of a new coronavirus infection in children
- Authors: Turovskaya A.A.1,2, Kostina E.M1, Orlova E.A1, Trushina E.Y.1, Grishanovich G.M2, Sidorova O.G2, Avdoshina E.V2
-
Affiliations:
- Penza Institute for Advanced Medical Education - Branch Campus of the Russian Medical Academy of Continuous Professional Education
- City Children's Polyclinic
- Issue: Vol 29, No 9 (2022)
- Pages: 57-61
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/321064
- DOI: https://doi.org/10.18565/pharmateca.2022.9.57-61
- ID: 321064
Cite item
Open Access
Access granted
Abstract
Background. Commonly, a new coronavirus infection in the pediatric population is characterized by an asymptomatic or oligosymptomatic course, in contrast to adults. The most common symptoms of COVID-19 in children include fever, catarrhal signs, intoxication of varying severity. Objective. Analysis of the clinical course of a new coronavirus infection in children in outpatient settings. Methods. An analysis of 78 case histories of children with COVID-19 who were treated in the Penza City Children’s Polyclinic, Children’s Polyclinic № 3 from September 2020 to February 2021 was performed. Results. It was revealed that the mean age of patients was 8.8 years. There were 52 boys (66.7%), 26 girls (33.3%). Asymptomatic course was diagnosed in 10 (12.8%) children, mild severity - in 52 (66.7%), moderate severity - in 16 (20.5%) children. The mean duration of illness was 18.5 days. In children with moderate COVID-19 severity, broncho-obstructive syndrome with a protracted course dominated in the clinical picture. Conclusion. Coronavirus infection in children can occur with broncho-obstructive syndrome. The first episode of bronchial obstruction may be the debut of bronchial asthma, which requires dynamic monitoring by a pediatrician, consultation with an allergist-immunologist, and a comprehensive examination after a COVID-19 infection. Evaluation of the features of the course of the disease, as well as monitoring its long-term consequences, remains relevant today.
Keywords
Full Text
About the authors
Alina A. Turovskaya
Penza Institute for Advanced Medical Education - Branch Campus of the Russian Medical Academy of Continuous Professional Education; City Children's Polyclinic
Email: alinaziboreva@yandex.ru
Postgraduate student at the Department of Clinical Immunology and Allergology; Pediatrician Penza, Russia
E. M Kostina
Penza Institute for Advanced Medical Education - Branch Campus of the Russian Medical Academy of Continuous Professional EducationPenza, Russia
E. A Orlova
Penza Institute for Advanced Medical Education - Branch Campus of the Russian Medical Academy of Continuous Professional EducationPenza, Russia
E. Yu Trushina
Penza Institute for Advanced Medical Education - Branch Campus of the Russian Medical Academy of Continuous Professional EducationPenza, Russia
G. M Grishanovich
City Children's PolyclinicPenza, Russia
O. G Sidorova
City Children's PolyclinicPenza, Russia
E. V Avdoshina
City Children's PolyclinicPenza, Russia
References
- Dong Y., Mo X., Hu Y., et al. Epidemiological characteristics of 2143 pediatric patients with 2019 Coronavis Disease in China. Pediatrics. 2020;145(6). doi: 10.1542/peds.2020-0702.
- Намазова-Баранова Л.С. Коронавирусная инфекция (Covid-19) у детей (состояние на апрель 2020). Педиатрическая фармакология. 2020;17(2):85-94. doi: 10.15690/pf.v17i2.2094.
- Snape M.D., Viner R.M. COVID-19 in children and young people. Science. 2020;370(6514):286-88. doi: 10.1126/science.abd6165
- URL: https://coronavirusonline.com.ua/countries/
- URL: https://www.rospotrebnadzor.ru/about/info/predpr/news_predpr.php?ELEMENT_ID=15344&sphrase_id=3165929
- URL: https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/
- Временные методические рекомендации: особенности клинических проявлений и лечения заболевания, вызванного новой коронавирусной инфекцией (COVID-19) у детей. Версия 2 (03.07.2020) (Электронный ресурс). URL: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/050/914/original/03062020_%D0%B4%D0%B5%D1%82%D0%B8_COVID-19_v2.pdf
- Alsohimea E., Temsaha M-H., Al-Nemri A.M., et al. COVID-19 infection prevalence in pediatric population: Etiology, clinical presentation, and outcome. J Infect Public Health. 2020;13:1791-96. doi: 10.1016/j.jiph.2020.10.008.
- Mehta N.S., Mytton O., Mullins E., et al. SARS-CoV-2 (COVID-19): What do we know about children? A systematic review. Lancet Inrect Dis. 2020;9(71):2469-79. doi: 10.1093/cid/ciaa556.
- Wu Q., Xing Y., Shi L., et al. Coinfection and other clinical characteristics of COVID-19 in children. Pediatrics. 2020;146(1):1-9. doi: 10.1542/peds.2020-0961.
- Tagarro A., Epalza C., Santos M., et al. Screening and severity of coronavirus disease 2019 (COVID-19) in children in Madrid, Spain. JAMA Pediatr. 2020;174(10):1009. doi: 10.1001/jamapediatrics.2020.1528.
- Miri S.M., Noorbakhsh E., Mohebbi S.R., Ghaemi A. Higher prevalence of asymptomatic or mild COVID-19 in children, claims and clues. J Med Virol. 2020;92(11):1-3. doi: 10.1002/jmv.26069
- Заплатников А.Л., Свинцицкая В.И. COVID-19 и дети. Русский медицинский журнал. 2020;6:20-2.
- Suratannon N., Dik W.A., Chatchatee P., Hagen PM. COVID-19 in children: Heterogeneity within the disease and hypothetical pathogenesis. Asian Pac J Allergy Immunol. 2020;38:170-77. doi: 10.12932/AP-170720-0920.
- Bunyavanich S., Do A., Vicencio A. Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults. JAMA. 2020;323(23):2427-29. doi: 10.1001/jama.2020.8707.
- Moeller A., Thanikkel L., Duijts L., et al. COVID-19 in children with underlying chronic respiratory diseases: survey results from 174 centres. ERJ Open Research. 2020;6(4):00409-2020. doi: 10.1183/23120541.00409-2020.
- Cardona-Hernandez R., Cherubini V., Iafusco D., et al. Children and youth with diabetes are not at increased risk for hospitalization due to COVID-19. Pediatr Diabetes. 2021;22:202-6. doi: 10.1111/pedi.13158.
- Александрович Ю.С., Байбарина Е.Н., Баранов А.А. и др. Ведение детей с заболеванием, вызванным новой коронавирусной инфекцией (SARS-CoV-2). Педиатрическая фармакология. 2020;17(2):103-18. doi: 10.15690/pf.v17i2.2096.
- Ramakrishnan S., Nicolau D.V., Langford B., Mahdi M. Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial. Lancet Respir Med. 2021;9(7):763-72. doi: 10.1016/S2213-2600(21)00160-0.
- Castro-Rodriguez J.A. Asthma and COVID-19 in children: A systematic review and call for data. Pediatr Pulmonol. 2020;55(9):2412-18. doi: 10.1002/ppul.24909.
- Arden K.E., Chang A.B., Lambert S.B., et al. Newly identified respiratory viruses in children with asthma exacerbation not requiring admission to hospital. J Med Virol. 2010;82:1458-61. doi: 10.1002/jmv.21819.
Supplementary files
