Effective methods of treatment of “thin” endometrium in patients of reproductive age

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Abstract

This article provides an analysis of the data presented in the world literature regarding the role of the endometrium in terms of reproductive failures, as well as modern methods of treating infertility caused by uterine factor. The review includes the results of studies and meta-analyses published in PubMed journals on this topic. The combination of many factors that affect the effectiveness of the interaction between the embryo and endometrial tissue makes it difficult to identify the true causes of reproductive failure in patients with uterine factor infertility. To date, the main methods of treating infertility associated with thinning of the endometrium are aimed at stimulating its growth and improving the blood supply to the uterus. A relatively new, but very promising direction in modern regenerative and reproductive medicine is the use of autologous platelet-rich plasma (Platelet-Rich Plasma – PRP) in patients with reproductive failures.

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About the authors

Zulfiya N. Efendieva

MOSITALMED International Medical Center

Author for correspondence.
Email: efendievaz@yandex.ru
ORCID iD: 0000-0002-2978-043X

Cand. Sci. (Med.), obstetrician-gynecologist

Russian Federation, Moscow

D. S. Makovskaya

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

Email: efendievaz@yandex.ru
ORCID iD: 0000-0003-0159-8641
Russian Federation, Moscow

I. A. Apolikhina

V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: efendievaz@yandex.ru
ORCID iD: 0000-0002-4581-6295
Russian Federation, Moscow; Moscow

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