Comparative characteristics of the incidence of various endocrinopathies in cancer patients receiving treatment with immune checkpoint inhibitors

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Abstract

To date, there are at least 6 national and international guidelines for the management of endocrine complications associated with the use of immune checkpoint inhibitors (ICPIs). This article is a summary of the latest guidelines developed by a number of scientists on behalf of the European Society of Endocrinology (ESE). The article presents possible endocrine complications during therapy with anti-CTLA-4, anti-PD-1, anti-PD-L1 drugs and combination treatment with ipilimumab and nivolumab. Combination treatment with ICPIs with chemotherapy or targeted therapy is not discussed in the guidelines and article.

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About the authors

I. B. Zhurtova

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov

Author for correspondence.
Email: zhin07@mail.ru
ORCID iD: 0000-0003-0668-1073

Dr. Sci. (Med.), Professor at the Department of Faculty Therapy

Russian Federation, Nalchik

L. S. Aramisova

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov

Email: zhin07@mail.ru
ORCID iD: 0000-0001-8105-4235
Russian Federation, Nalchik

H. A. Abdul Moati

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov

Email: zhin07@mail.ru
ORCID iD: 0009-0009-4374-8442
Russian Federation, Nalchik

D. R. Arkhestova

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov

Email: zhin07@mail.ru
ORCID iD: 0000-0002-5490-4166
Russian Federation, Nalchik

E. Z. Khachmakhova

Department of Faculty Therapy, Medical Academy, Kabardino-Balkarian State University n.a. Kh.M. Berbekov

Email: zhin07@mail.ru
ORCID iD: 0009-0006-6537-3969
Russian Federation, Nalchik

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