Features of the course of dermatoses against the background of HIV infection

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Abstract

The article provides data on the human immunodeficiency virus (HIV), a slowly progressive infectious disease that occurs as a result of HIV infection and affects the immune system, as a result of which the body becomes highly susceptible to opportunistic infections and tumors, leading to the death of the patient. The etiology, pathogenesis and clinical classification of HIV infection are discussed in detail. At the early stages of HIV infection, skin diseases often become a marker of the course of the disease and pose a serious problem. Cutaneous manifestations often reflect compromised immune status, which contributes to understanding long-term prognosis. With the advent of antiretroviral therapy, mortality from skin diseases, in particular from opportunistic infections, has decreased. However, serious dermatological problems still exist. The article provides data on concomitant diseases of HIV-infected patients. The clinical and pathogenetic features of diseases common among the general population (seborrheic dermatitis, psoriasis, vasculitis, fungal and herpetic infections), often with increased prevalence or severity in HIV-positive people, are discussed in detail.

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About the authors

L. A. Yusupovа

Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education

Author for correspondence.
Email: yuluizadoc@hotmail.com
ORCID iD: 0000-0001-8937-2158
SPIN-code: 5743-6872

Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology

Russian Federation, Kazan

Z. Sh. Garaeva

Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education

Email: yuluizadoc@hotmail.com
ORCID iD: 0000-0001-9096-0563
SPIN-code: 3156-8170
Russian Federation, Kazan

E. I. Yunusovа

Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education

Email: yuluizadoc@hotmail.com
ORCID iD: 0000-0002-4550-9578
SPIN-code: 8514-0058
Russian Federation, Kazan

G. I. Mavlyutova

Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education

Email: yuluizadoc@hotmail.com
ORCID iD: 0000-0002-4652-8869
SPIN-code: 3427-8924
Russian Federation, Kazan

References

  1. Клинические рекомендации. ВИЧ-инфекция у взрослых. 2022. C. 11–15. [Clinical guidelines. HIV infection in adults. 2022. P. 11–5. (In Russ.)].
  2. Позднякова О.Н., Бычков С.Г., Немчанинова О.Б., Решетникова Т.Б. Патология кожи и слизистых оболочек у детей с ВИЧ-инфекцией. Фарматека. 2023;13:14–8. [Pozdnyakova O.N., Bychkov S.G., Nemchaninova O.B., Reshetnikova T.B. Pathology of the skin and mucous membranes in children with HIV infection. Farmateka. 2023;13:14–8. (In Russ.)]. doi: 10.18565/pharmateca.2023.13.14-18.
  3. Беляков Н.А., Рассохин В.В., Розенталь В.В. и др. Эпидемиология ВИЧ-инфекции. Место мониторинга, научных и дозорных наблюдений, моделирования и прогнозирования обстановки. ВИЧ-инфекция иммуносупрессии. 2019;11(2):7–26 [Belyakov N.A., Rassohin V.V., Rozental’ V.V., et al. Epidemiology of HIV infection. Place of monitoring, scientific and sentinel observations, modeling and forecasting of the situation. VICh-infekciya iimmunosupressii. 2019;11(2):7–26. (In Russ.)].
  4. Пасечник О.А., Левахина Л.И., Магар Н.И. и др. ВИЧ-инфекция в омской области: динамика и структура заболеваемости населения. Медицинский альманах. 2022;3(72):70. [Pasechnik O.A., Levahina L.I., Magar N.I., et al. HIV infection in the Omsk region: dynamics and structure of morbidity among the population.Medicinskij al’manah. 2022;3(72):70. (In Russ.)].
  5. Покровский В.В., ред. ВИЧ-инфекция и СПИД. Национальное руководство. М.: ГЭОТАР-Медиа, 2020. C. 24–35. [Pokrovsky V.V., ed. HIV infection and AIDS. National leadership. M.: GEOTAR-Media, 2020. P. 24–35. (In Russ.)].
  6. Хрянин А.А., Стуров В.Г., Шпикс Т.А., Пушкарев Е.В. Клинический случай себорейного дерматита и тяжелой формы ВИЧ-инфекции с особенностями психологического профиля пациента. Фарматека. 2022;10:98–103. [Khryanin A.A., Sturov V.G., Shpiks T.A., Pushkarev E.V. A clinical case of seborrheic dermatitis and a severe form of HIV infection with features of the patient’s psychological profile. Farmateka. 2022;10:98–103. (In Russ.)]. doi: 10.18565/pharmateca.2022.10.98-103.
  7. Юсупова Л.А. Современный взгляд на проблему старения кожи. Лечащий врач. 2017;6:75. [Yusupova L.A. Modern view on the problem of skin aging. Lechashchii vrach. 2017;6:75. (In Russ.)].
  8. Архипов К.В., Фридман Е.А. Клинический случай: генерализованная саркома капоши у ВИЧ-инфицированного пациента. E-Scio. 2022;11(74):56–9 [Arhipov K.V., Fridman E.A. Clinical case: generalized Kaposi’s sarcoma in an HIV-infected patient. E-Scio. 2022;11(74):56–9. (In Russ.)].
  9. Евдокимов Е.Ю., Понежева Ж.Б., Сундуков А.В., Свечникова Е.В. Влияние воспалительных дерматозов на качество жизни ВИЧ-позитивных пациентов. Фарматека. 2020;14:109–12. [Еvdokimov E.Yu., Ponezhe-va Zh.B., Sundukov A.V., Svechnikova E.V. The impact of inflammatory dermatoses on the quality of life of HIV-positive patients. Farmateka. 2020;14:109–12. (In Russ.)]. doi: 10.18565/pharmateca.2020.14.109-112.
  10. Соломонник О.Н. Проявление кожных изменений у больных ВИЧ-инфекцией. Экономика и социум. 2022;8(99):323–26 [Solomonnik O.N. Manifestation of skin changes in patients with HIV infection. Ekonomika i socium. 2022;8 (99):323–26. (In Russ.)].
  11. Федотов В.П. Кожные проявления при ВИЧ-инфекции (клиническая лекция). ДВКС. 2020:126–30. [Fedotov V.P. Skin manifestations in HIV infection (clinical lecture). DVKS. 2020:126–30. (In Russ.)].
  12. Клинические рекомендации. Себорейный дерматит. 2022. С. 5–9. [Clinical practice guidelines. Seborrheic dermatitis. 2022. Р. 5–9. (In Russ.)].
  13. Юсупова Л.А. Современное состояние проблемы эксфолиативного дерматита. Лечащий врач. 2019;11:6–8 [Yusupova L.A. The current state of the problem of exfoliative dermatitis. Lechashchii vrach. 2019;11:6–8. (In Russ.)].
  14. Cimbetete T., Bak K., Choshi P. et al. HIV-associated immune dysregulation in the skin: a test for excessive inflammation and hypersensitivity. J Res Dermatol. 2023;143(3):362–73.
  15. Евдокимов Е.Ю., Понежева Ж.Б., Свечникова Е.В., Груздев Б.М. Опыт применения препарата нетакимаб для лечения псориаза у ВИЧ-инфицированных больных. Фарматека. 2022;8:91–6. [Evdokimov E.Yu., Ponezheva Zh.B., Svechnikova E.V., Gruzdev B.M. Experience with the use of netakimab for the treatment of psoriasis in HIV-infected patients. Farmateka. 2022;8:91–6. (In Russ.)]. doi: 10.18565/pharmateca.2022.8.91-96.
  16. Armani M., Arbyte A.A., Nicol kate, Angel, Faced, Natural. Therapeutic problems of psoriasis in an HIV-infected patient: a clinical case. 2022;23(2):175.
  17. Теохарова Л.С. Особенности течения псориаза у ВИЧ-инфицированных пациентов. Science Time. 2023;7(114):23–6 [Teoharova L.S. Features of the course of psoriasis in HIV-infected patients. Science Time. 2023;7(114):23–6. (In Russ.)].
  18. Guillevin L. Vasculitis in the context of HIV infection. AIDS. 2008;22 (3):27–33.
  19. Юсупова Л.А. Современное состояние проблемы ангиитов кожи. Лечащий врач. 2013;5: 38. [Yusupova L.A. Current state of the problem of skin angiitis. Lechashchij vrach. 2013;5:38. (In Russ.)].
  20. Chetti R. Vasculitis associated with HIV infection. J Clin Pathol. 2001;54(4):275–78.
  21. Грекова Ю.Н., Кохан М.М., Куклин И.А., Торопова Н.П., Игликов В.А. Экстрамаммарная болезнь Педжета у ВИЧ-инфицированной пациентки (клиническое наблюдение). Клинический разбор в общей медицине. 2022;6:48–50 [Grekova Yu.N., Kohan M.M., Kuklin I.A., Toropova N.P., Iglikov V.A. Extramammary Paget’s disease in an HIV-infected patient (clinical observation).Klinicheskij razbor v obshchej medicine. 2022;6:48–50. (In Russ.)].
  22. Нагибина М.В., Мартынова Н.Н., Преснякова О.А. и др. Особенности клиники и лечения поражений кожи при ВИЧ-инфекции. Лечащий врач. 2015;2:83. [Nagibina M.V., Martynova N.N., Presnyakova O.A., Vdovina E.T., Gruzdev B.M. Features of the clinical picture and treatment of skin lesions in HIV infection. Lechashchij vrach. 2015;2:83. (In Russ.)].

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