The role of essential phospholipids in the complex therapy of non-alcoholic fatty liver disease: a case-control study

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Abstract

Background. The article demonstrates the potentiation of the clinical effect of essential phospholipids (EPLы) in relation to liver fibrosis in non-alcoholic fatty liver disease (NAFLD), when using complex therapy for NAFLD that meets current specialized clinical guidelines, with the inclusion of EPL in the treatment regimen.

Objective. Comparative assessment of liver stiffness after EPL therapy and without the use of EPL in the context of compliance with specialized clinical guidelines.

Methods. All patients received adequate therapy for NAFLD. In 58 patients, the drug from the EPL group was included in the treatment regimen (experimental group), in 52 patients, the drug was not included (control group).

Results. The presence of a statistically significant difference was determined between patients who received treatment with and without the use of EPL in the regimen.

Conclusion. It is recommended to include EPL in the complex therapy of NAFLD.

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About the authors

Larisa V. Tarasova

I.N. Ulyanov Chuvash State University

Author for correspondence.
Email: tlarisagast18@mail.ru
ORCID iD: 0000-0003-1496-0689
Scopus Author ID: 35777248600

Dr. Sci. (Med.), Head of the Department of Hospital Therapy

Russian Federation, Cheboksary

Yulia V. Tsyganova

I.N. Ulyanov Chuvash State University

Email: tlarisagast18@mail.ru
ORCID iD: 0000-0002-8339-9496

Candidate of Medical Sciences, Associate Professor of the Department of Hospital Therapy

Russian Federation, Cheboksary

Igor Yu. Fillipov

I.N. Ulyanov Chuvash State University

Email: tlarisagast18@mail.ru
ORCID iD: 0000-0001-7653-1068

senior lecturer of the Department of Hospital Therapy

Russian Federation, Cheboksary

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2. Fig. Analysis of liver stiffness values ​​after treatment depending on the fact of taking EFL

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