Determination of catecholamine levels in patients with chronic pelvic pain associated with endometriosis

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Abstract

Background. Chronic pelvic pain in endometriosis is accompanied by high levels of stress and anxiety.

Objective. Evaluation of the norepinephrine, adrenaline levels in the peripheral blood of patients with chronic pelvic pain and endometriosis.

Methods. A comparative analysis of the results of assessing blood catecholamine levels and stress levels was performed in 40 women (18-45 years old) with endometrioid ovarian cysts suffering from chronic pelvic pain and neuropathy.

Study design: comparative prospective study.

Results. Patients with chronic pelvic pain associated with endometriosis had high blood catecholamine levels compared with the control group and the group with painless endometriosis (p < 0.05).

Conclusion. High levels of stress, anxiety and depression in patients with CPP and endometriosis maintain high blood levels of adrenaline and norepinephrine, aggravating chronic pain.

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About the authors

A. S. Chernetsova

Clinical and Diagnostic Center

Author for correspondence.
Email: ana550@mail.ru
ORCID iD: 0000-0001-9451-6371

Obstetrician-Gynecologist

Russian Federation, Moscow

M. N. Sharov

Russian University of Medicine

Email: ana550@mail.ru
ORCID iD: 0000-0001-9634-346X
Russian Federation, Moscow

L. V. Adamyan

Russian University of Medicine

Email: ana550@mail.ru
ORCID iD: 0000-0002-3253-4512
Russian Federation, Moscow

K. D. Murvatov

Main Military Clinical Hospital of the National Guard Troops of the Russian Federation

Email: ana550@mail.ru
Russian Federation, Balashikha, Moscow Region

S. I. Kiselev

Filatov City Clinical Hospital No. 15

Email: ana550@mail.ru
ORCID iD: 0000-0002-6872-4721
Russian Federation, Moscow

Yu. S. Prokofieva

Filatov City Clinical Hospital No. 15

Email: ana550@mail.ru
ORCID iD: 0000-0003-4454-7174
Russian Federation, Moscow

I. N. Goncharov

Medical Center of the Goncharov Medical Dynasty

Email: ana550@mail.ru
ORCID iD: 0000-0002-4513-6476
Russian Federation, Moscow

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