Comorbidity of erosive gastroesophageal reflux disease and irritable bowel syndrome. Clinical case

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Background: Currently, significant importance is attached to comorbidity in gastrointestinal diseases. Comorbidity of gastroesophageal reflux disease and irritable bowel syndrome is associated with the presence of common pathophysiological mechanisms and is associated with a decrease in the quality of life.

Description of the clinical case: The article considers a clinical case of overlap syndrome of gastroesophageal reflux disease with erosive esophagitis and irritable bowel syndrome in a 37-year-old patient, as well as the effectiveness of therapy using a proton pump inhibitor and a selective myotropic antispasmodic in this case.

Conclusion: The combination of a PPI (pantoprazole) and a selective myotropic antispasmodic (mebeverine hydrochloride) can be considered when choosing therapy in comorbid patients.

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作者简介

Irina Kozlova

Saratov State Medical University named after V.I. Razumovsky

Email: jdipisma@mail.ru
ORCID iD: 0000-0002-5056-4504
SPIN 代码: 7995-5124
Scopus 作者 ID: 7102626490
Researcher ID: B-2802-2017
俄罗斯联邦, Saratov

Tatyana Tikhonova

Saratov State Medical University named after V.I. Razumovsky

编辑信件的主要联系方式.
Email: jdipisma@mail.ru
ORCID iD: 0000-0002-0981-1083
SPIN 代码: 4101-1360
Scopus 作者 ID: 57339702600
Researcher ID: AAA-9469-2021

Associate Professor, Department of Therapy, Gastroenterology and Pulmonology

俄罗斯联邦, Saratov

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