USE OF ENTEROFURIL SUSPENSION IN THE TREATMENT OF DISEASES ASSOCIATED WITH HELICOBACTERIOSIS


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Abstract

The issues of evolution of antihelicobacter therapy in recent years are considered. One of the problems in this area is the increasing resistance of Helicobacter pylori to metronidazole - a standard component of eradication therapy. In this regard, the Central Research Institute of Gastroenterology has been developed and tested a scheme of eradication therapy, including proton pump inhibitor, antibiotic clarithromycin, and Enterofuril® (nifuroxazide) as a third component. The article presents the results of study included 120 adult patients with H. pylori infection and various diseases of upper digestive tract treated with 7-day eradication therapy involving pantoprazole 20 mg twice a day, clarithromycin 500 mg 2 times a day, and Enterofuril or metronidazole as a third component. It was shown that the triple therapy of helicobacteriosis including suspension Enterofuril is very effective eradication scheme in adults, with superior to scheme with metronidazole efficacy and tolerability.

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