Opyt primeneniya preparata Ingaron® (interferon gamma chelovecheskiy rekombinantnyy) v lechenii luchevykh tsistitov, soprovozhdayushchikhsya gematuriey
- Authors: Kaprin A.D1, Kostin A.A1, Semin A.V1, Nesterov P.V1
-
Affiliations:
- Issue: No 12 (2013)
- Pages: 37-40
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/282253
- ID: 282253
Cite item
Open Access
Access granted
Abstract
Radiation therapy of the pelvic organs may be accompanied by the development of radiation reactions and bladder complications. Clinical manifestation of radiation cystitis is similar to that of banal cystitis. According to the data of some authors, the frequency of hemorrhagic cystitis induced by radiation therapy varies from 5,7 to 11,5 % and can appear from 2 months to 10 years after radiation exposure. Currently, immunomodulating drugs with multipurpose activity are widely used in the treatment of infectious and inflammatory diseases of the urinary tract, including radiation-induced disorders. The use of interferon-Y Ingaron® has a positive therapeutic effect in the treatment of complex forms of late hemorrhagic radiation cystitis.
Keywords
Full Text
References
- Иваницкая В.И., Кисличенко В.А., Геринштейн И.Г. и др. Осложнения лучевой терапии у онкологических больных. К., 1989. 174 с.
- Бардычев М.С., Белая И.С, Гунько О.И., и др. Поздние лучевые повреждения после комплексного лечения рака шейки и тела матки / Материалы Всероссийской научнопрактической конференции «Роль лучевой терапии в гинекологической онкологии». Обнинск, 2002. С. 31.
- Каприн А.Д., Иванов С.А., Клименко А.А. Уроантисептическая терапия в лечении лучевого цистита у женщин. М., 2005.
- Shiels RA, Nissenbaum MM, Mark SR, Browde S. Late radiation cystits after treatment for carcinoma of the bladder. S Afr Med 1986; 70:727-28.
- Van Merkesteyn JP, Bakker DJ, Kooijman R. Radionecrosis. Handbook of hyperbaric medicine. Berlin, 1996:396-97.
- Neheman A, Nativ O, Moskovitz B, et al. Hyperbaric oxygen therapy for radiation-induced haemorrhagic cystitis. BJU Int 2005;96:107-9.
- Radiotherapy in Cancer Management. A practical manual. Chapman & Hall medical, 1997:160-61.
- Киселева Е.С., Голдобенко Г.В., Канаева С.В. и др. М., 1996. С. 437-445, 457.
- Caeiro Munoz M, Calderon Gonzalez A, Mojon Ojea Apapela. Oxigenoterapia hiperbarica en el tratamiento de las complicaciones cronicas derivadas del tratamiento con radioterapia en pacientes con cancer. Bases fisicas, tecnicas y clinicas. Oncologia 2005;28:20-9.
- Galalae M, Kovacs G, Schultza J, et al. Long term outcome after elective irradiation of the pelvic lymphatics and local dose escalation using high dose-rate brachyterapy for locally advanced prostate cancer. int J radiat Oncol Biol Phys. 2002;52:81-90.
- Lawton CA, Won M, Pilepich MV, et al. Longterm treatment sequelae following external beam irradiation for adenocarcinoma of the prostate: analysis of RTOG studies 7506 and 7706. int J radiat Oncol Biol Phys 1991; 21:935-39. патологией, такой как поздний лучевой цистит, сопровождающийся гематурией.
- Kaplan JR, Wolf JS. Efficacy and survival associated with cystoscopy and clot evacuation for radiation or cyclophosphamide induced hemorrhagic cystitits. J Urol 2009;181:641-46.
- Bevers RFM, Bakker DJ, Kurth K. Hyperbaric oxygen treatment for haemorrhagic radiation cystitis. Lancet 1995;346:803-05.
- Weiss J, Mattei D, Neville E, Hanno P. Primary treatment of radiation induced hemorrhagic cystitis with hyperbaric oxygen: 10-year experience. J Urol 1994;151:1514-17.
- Neheman A, Nativ O, Moskovitz B, et al. Hyperbaric oxygen therapy for radiation-induced haemorrhagic cystitis. Br J Urol Int 2005;96:107-09.
- Галил-Оглы Г.А., Каприн А.Д., Титова В.А., и др. Функциональные и морофологические изменения нижних мочевых путей в процессе лучевой терапии на органы малого таза. М., 2004.
- Пушкарь Д.Ю., Касян Г.Р. Новое в лечении хронического простатита: интерферон-гамма // Фарматека 2012. № 4. С. 1-3.
Supplementary files
