Sovremennye vozmozhnosti mukoaktivnoy terapii
- Authors: Zaytsev A.A1, Okovityy S.V1, Kryukov E.V1
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- Issue: No 14 (2015)
- Pages: 81-85
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/288161
- ID: 288161
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Abstract
The article considers the principles of application of mucoactive drugs, which include mucokinetics, mucolytics, mucoregulators, as well as drugs reducing or maintaining the functional activity of the ciliary cells of the bronchial mucosa - stimulators of mucociliary clearance. There are two groups among mucolytics and mucoregulators: drugs realizing its effect mainly in the lumen of the bronchi (bromhexine, ambroxol, guaifenesin), and preparations normalizing the formation of bronchial secretions (acetylcysteine, dornase alpha). In cases when patients have several symptoms of affect of the tracheobronchial tree (eg, cough, presence of viscous sputum, bronchial obstruction), it is reasonable to use the combined mucoactive drugs such as Ascoril containing mucolytic (Bromhexine), mucolytic/mucokinetic (guaifenesin) and ß2-adrenoagonist (salbutamol).
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References
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