HCV-ASSOCIATED LIVER CIRRHOSIS: MODERN POSSIBILITIES OF INTERFERON-FREE THERAPY


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Abstract

The article presents the results of combination therapy using antiviral drugs with direct action as follows: daclatasvir 60 mg 1 time a day plus asunaprevir 100 mg twice a day for 24 weeks with the participation of 29 cirrhotic patients in the outcome of chronic hepatitis C with 1b-genotype. Results of use of interferon-free combination asunaprevir+daclatasvir allows to consider it as a safe and effective scheme of choice in patients with HCV-associated liver cirrhosis.

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About the authors

I. G Bakulin

SBHCI “Moscow Clinical Research Center" of Moscow Healthcare Department

Email: igbakulin@yandex.ru
MD, Prof., Head of the Department of Hepatology Moscow

D. T Abdurakhmanov

SBEI HPE “First MSMU n.a.I.M.Sechenov" of RMPH; MSU n.a. M.I. Lomonosov

Moscow

N. V Shalikiani

SBHCI “Moscow Clinical Research Center" of Moscow Healthcare Department

Moscow

A. V Polukhina

SBHCI “Moscow Clinical Research Center" of Moscow Healthcare Department

Moscow

Yu. A Matveeva

SBHCI “Moscow Clinical Research Center" of Moscow Healthcare Department

Moscow

E. I Sidorova

MSU n.a. M.I. Lomonosov

Moscow

T. P Rozina

SBEI HPE “First MSMU n.a.I.M.Sechenov" of RMPH

Moscow

E. N Nikulkina

SBEI HPE “First MSMU n.a.I.M.Sechenov" of RMPH

Moscow

References

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