Spontaneous regression of lumbar disc herniations against the background of therapy with gabapentin
- Authors: Tkachev A.M1, Akarachkova E.S2, Smirnova A.V1, Ilyushin A.V1, Kulyutkin N.V3, Smerya Y.V4
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Affiliations:
- OOO MDC MIBS
- International Society “Stress Under Control"
- NGHCI RCH at the Volgograd-1 station of OAO Russian Railways
- SHCI CH № 4, Volgograd
- Issue: No 19 (2017)
- Pages: 20-24
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/290028
- ID: 290028
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Abstract
Herniated intervertebral discs (HID) are the most common pathology among degenerative-dystrophic diseases of the musculoskeletal system, which in recent years are increasingly occurred in persons of young, active working age. The article presents observations of three patients who had a rapid regression of lumbar disc herniations against the background of therapy with gabapentin. The main pathophysiological mechanisms allowing to explain the mechanism of resorption (dehydration of the gelatinous nucleus, retraction of the intervertebral disc with a hernia back into the space occupied by it in norm, enzymatic destruction and phagocytosis of the cartilaginous tissue), as well as the role of gabapentin in this process are discussed.
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About the authors
A. M Tkachev
OOO MDC MIBS
E. S Akarachkova
International Society “Stress Under Control"
Email: nevrorus@mail.ru
MD, President
A. V Smirnova
OOO MDC MIBS
A. V Ilyushin
OOO MDC MIBS
N. V Kulyutkin
NGHCI RCH at the Volgograd-1 station of OAO Russian Railways
Yu. V Smerya
SHCI CH № 4, Volgograd
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