CLINICAL CASE OF SEVERE MYOCARDIAL DAMAGE IN A PATIENT WITH GIPOPITUITARISM


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Background. Hypopituitarism - HP (pituitary insufficiency) is a disease caused by loss of function of tropic hormones (tropins) of the anterior lobe of the pituitary gland and manifested by a deficiency in the function of the peripheral endocrine glands. There are the following types of HP: isolated - reducing the secretion of one tropic hormone; partial - combined loss of function of several tropic hormones; and total (panhypopituitarism) and hypothalamic-pituitary insufficiency - a combination of HP and diabetes insipidus. Among the main causes of HP special mention should go to adenomas and tumors of the pituitary gland and hypothalamus or other parts of the central nervous system, congenital pituitary aplasia, sarcoidosis, tuberculosis, syphilis, inflammatory brain diseases, vascular disorders in the arteries supplying the pituitary gland and the hypothalamus. Description of the clinical case. The article presents a clinical observation of a patient with myocardial damage (probable infectious myocarditis) and HP. Conclusion. The lack of literature data and, accordingly, the lack of clinical experience in the management of such patients make this case unique.

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作者简介

V. Sergeeva

Saratov State Medical University n.a. V.I. Razumovsky

Email: yiktoriasergeeva@mail.ru
PhD, Teaching Assistant at the Department of Hospital Therapy of the Faculty of Medicine

E. Zhukova

Regional Clinical Hospital, Saratov

L. Bogdalova

Saratov State Medical University n.a. V.I. Razumovsky

Yu. Kharkova

Saratov State Medical University n.a. V.I. Razumovsky

参考

  1. Hall R. Diagnosis and management of hypopituitarism. J. Royal Coll. Physic. London. 1972;7:19-33.
  2. De-GennesJ.L., Turpin G., Heshmati H.M., Lebrun A. Hypopituitarisme et hyperlipidemie. Effet preventif du deficit somatotrope sur le developpement de l'atherosclerose. A propos de 12 observations. Ann. Endocrinol. Paris. 1979;40:557-58.
  3. Gutiérrez L.P., Koftowska-Häggström M., Jönsson PJ., et ai. Westberg B., Luger A. Registries as a tooi in evidence-based medicine: example of KIMS (Pfizer International Metabolic Database). Pharmacoepidemioi. Drug Saf. 2008;17(1):90-102. doi: 10.1002/pds.1510.
  4. Seppard M.C., Steward PM. Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet. 2001;357:425-31.
  5. Prabhakar V.K.B., Shalet S.M. Aetiology, diagnosis, and management of hypopituitarism in adult life. Postgraduate Med. J. 2006;82(966):259-66. doi: 10.1136/pgmj.2005.039768.
  6. Bulow B., Hagmar L., Eskilsson J., Erfurth E.M. Hypopituitary females have a high incidence of cardiovascular morbidity and an increased prevalence of cardiovascular risk factors. J. Clin. Endocrinol. Metab. 2000;85:574-84.
  7. Rosen T., Bengtsson B. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet. 1990:336:285-88.
  8. Beshyah S.A., Johnston D.G. Cardiovascular disease and risk factors in adults with hypopituitarism. Clin. Endocrinol. 1999;50:1-15.
  9. Blackett P.R., Weech R.K., McConathy W.J., Fesmire J.D. Growth hormone in the regulation of hyperlipidemia. Metabolism. 1982;31:117-20.
  10. Al-Shoumer K.A.S., Cox K.H., Hughes C.L., Richmond W., Johnston D.G. Fasting and postprandial lipid abnormalities in hypopituitary women receiving conventional replacement therapy. J. Clin. Endocrinol. Metabol. 1997;82:2653-59.
  11. Landin-Wilhelmsen K., Tengborn L., Wilhelmsen L., Bengtsson B.-A. Elevated fibrinogen levels decrease following treatment of acromegaly. Clin. Endocrinol. 1997;46:69-74.

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