Clinical significance of morphological ultrastaging in breast and uterine cancer

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The condition of the lymph nodes is an important prognostic factor and criterion for adjuvant therapy in malignant neoplasms (MN), while the detection of micrometastases using ultrastaging methods correlates with a poor prognosis in a number of MN and is part of the standard treatment of patients with such a pathology as skin melanoma. In such nosologies as carcinoma of the corpus uteri, breast and colon, ultrastaging of the lymph nodes remains a subject of discussion. The significance of ultrastaging of the sentinel lymph node in choosing treatment tactics for breast cancer and reducing the risk of locoregional recurrence remains a subject of discussion.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Gulnoz Khakimova

Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology; Tashkent Pediatric Medical Institute

Хат алмасуға жауапты Автор.
Email: hgg_doc@mail.ru
ORCID iD: 0000-0002-4970-5429

Associate Professor of the Department of Children Oncology, Palliative Care, Tashkent Pediatric Medical Institute; Oncologist of the Chemotherapy Department, Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology

Өзбекстан, Tashkent; Tashkent

Igor Reshetov

Sechenov First Moscow State Medical University; N.V. Sklifosovsky Institute of Clinical Medicine

Email: 2487784@mail.ru
ORCID iD: 0000-0002-0909-6278
SPIN-код: 3845-6604

Academician of RAS, Dr. Sci. (Med.), Professor, Director of the Levshin Institute of Cluster Oncology, I.M. Sechenov First Moscow State Medical University (Sechenov University); Head of the Department of Oncology, Radiotherapy and Reconstructive Surgeryof the N.V. Sklifosovsky Institute of Clinical Medicine

Ресей, Moscow; Moscow

A. Zikiryakhodjaev

National Medical Research Center of Radiology; I.M. Sechenov First Moscow State Medical University (Sechenov University); People’s Friendship University of Russia (RUDN University)

Email: hgg_doc@mail.ru
ORCID iD: 0000-0001-7141-2502

Dr. Sci. (Med.), Professor, Head of the Department of Reconstructive Plastic Surgery of the Breast and Skin, P.A. Herzen Moscow Research Oncology Institute – Branch of the National Medical Research Center of Radiology; Associate Professor of the Department of Oncology, People’s Friendship University of Russia (RUDN University)

Ресей, Moscow; Moscow; Moscow

Shakhnoz Khakimova

Tashkent Pediatric Medical Institute; National Medical Research Center of Radiology

Email: shahnoz_khakimova@mail.ru
ORCID iD: 0000-0002-9491-0413

Associate Professor of the Department of Pediatric Oncology, Tashkent Pediatric Medical Institute; Dr. Sci. (Med.), Trainee of the Department of Reconstructive Plastic Surgery of the Breast and Skin, P.A. Herzen Moscow Research Oncology Institute – Branch of the National Medical Research Center of Radiology

Өзбекстан, Tashkent; Moscow, Russia

Әдебиет тізімі

  1. Bézu C., Coutant C., Ballester M., et al. Ultrastaging of lymph nodes in uterine cancers. J Exp Clin Cancer Res. 2010;29:5. https://doi.org/10.1186/1756-9966-29-5
  2. Perry N., Broeders M., de Wolf C., et al. European guidelines for quality assurance in breast cancer screening and diagnosis. Fourth edition – Summary Document. Ann Oncol. 2008;19:614–22.
  3. Giuliano A.E., Hawes D., Ballman K.V., et al. Association of occult metastases in sentinel lymph nodes and bone marrow with early-stage invasive breast cancer. JAMA. 2011;306:385–93.
  4. Weaver D.L., Ashikaga T., Krag D.N., et al. Effect of occult metastases on survival in node-negative breast cancer. N Engl J Med. 2011;364:412–21.
  5. Weaver D.L., Le U.P., Dupuis S.L., et al. Metastasis detection in sentinel lymph nodes: comparison of a limited widely spaced (NSABP protocol B-32) and a comprehensive narrowly spaced paraffin block sectioning strategy. Am J Surg Pathol. 2009;33:1583–9.
  6. Colpaert C., Lambein K. Letter to the editor: concerning a previously published practice guideline article. Belg J Med Oncol. 2012;6:183–4.
  7. Bolster M.J., Pepels M.J., Wauters C.A.P., et al. Is the sentinel lymph node pathology protocol in breast cancer patients associated with the risk of regional recurrence? Eur J Sur Oncol. 2013;39(5):437–41.
  8. Nair I.R., Mathew A.J., Kottarathil V.D. Detection of micrometastasis in axillary lymph nodes of breast carcinoma patients and its association with clinical outcome. Indian J Pathol Microbiol. 2018;6:330–3.
  9. Kamath V.J., et al. Characteristics of the sentinel lymph node in breast cancer predict further involvement of higher-echelon nodes in the axilla: a study to evaluate the need for complete axillary lymph node dissection. Arch Surg. 2001;136(6):688–92.
  10. Frumovitz M., Sun C.C., Schmeler K.M., et al. Parametrial involvement in radical hysterectomy specimens for women with early-stage cervical cancer. Obstet Gynecol. 2009;114:93–9. https://doi.org/10.1097/AOG.0b013e3181ab474d
  11. Li C., Yang S., Hua K. Nomogram predicting parametrial involvement based on the radical hysterectomy specimens in early-stage cervical cancer. Front Surg. 2021;8:759026. https://doi.org/10.3389/fsurg.2021.759026
  12. Wright J.D., Grigsby P.W., Brooks R., et al. Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy. Cancer. 2007;110:1281–6. https://doi.org/10.1002/cncr.22899
  13. Colpaert C., Jacomen G., Van de Vijver K., et al. Belgian Working Group for Gynecological Pathology. Ultrastaging of sentinel lymph nodes in gynecological cancer: Repeating the story of breast cancer? Gynecol Oncol. 2019;152:202–7.
  14. Cibula D., McCluggage W.G. Sentinel lymph node (SLN) concept in cervical cancer: current limitations and unanswered questions. Gynecol Oncol. 2019;152:202–7.
  15. Cibula D., Abu-Rustum N.R., Dusek L., et al. Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer. Gynecol Oncol. 2012;124:496–501.
  16. Winter R., Haas J., Reich O., et al. Parametrial spread of cervical cancer in patients with negative pelvic lymph nodes. Gynecol Oncol. 2002;84:252–7. https://doi.org/10.1006/gyno.2001.6495
  17. Euscher E.D., Malpica A., Atkinson E.N., et al. Ultrastaging improves detection of metastases in sentinel lymph nodes of uterine cervix squamous cell carcinoma. Am J Surg Pathol. 2008;32(9):1336–43. https://doi.org/10.1097/PAS.0b013e31816ecfe4
  18. Lührs O., Ekdahl L., Geppert B., et al. Resection of the upper paracervical lymphovascular tissue should be an integral part of a pelvic sentinel lymph node algorithm in early-stage cervical cancer. Gynecol Oncol. 2021;163:289–93. https://doi.org/10.1016/j.ygyno.2021.08.031
  19. Balaya V., Bresset A., Guani B., Benoit L., et al. SENTICOL group. Pre-operative surgical algorithm: Sentinel lymph node biopsy as predictor of parametrial involvement in early-stage cervical cancer. Int J Gynecol Cancer. 2020;30:1317–25. https://doi.org/10.1136/ijgc-2020-001586
  20. Bizzarri N., Arciuolo D., Certelli C., et al. Ultrastaging of the parametrium in cervical cancer: A clinicopathological study. Cancers (Basel). 2023;15(4):1099. https://doi.org/10.3390/cancers15041099
  21. Ferrandina G., Anchora L.P., Gallotta V., et al. Can we define the risk of lymph node metastasis in early-stage cervical cancer patients? A large-scale, retrospective study. Ann Surg Oncol. 2017;24:2311–8. https://doi.org/10.1245/s10434-017-5917-0

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