PREVALIN V LEChENII SEZONNOGO ALLERGIChESKOGO RINITA

This study was aimed to the evaluation of the anti-inflammatory efficacy of combination of standard therapy of seasonal allergic rhinitis with the barrier preparation (Prevalin). The open perspective randomized comparative parallel-group study included 49 patients with moderate to severe seasonal allergic rhinitis caused by wormwood pollen sensitization. All patients were treated with intranasal glucocorticosteroids in combination with a non-sedating antihistamines, 30 patients additionally received Prevalin 4 times a day. The frequency and severity of symptoms during treatment, the need for drug therapy, standard laboratory parameters, the level of eosinophil cationic protein in serum and nasal contents were evaluated. The results showed that the use of Prevalin in addition to the standard pharmacotherapeutic complex promoted more rapid and effective suppression of disease symptoms, as well as support of pharmacological remission of the disease using a smaller volume of basic therapy. More rapid achievement of clinical effect was recorded against the background of a more effective suppression of allergic inflammation.

seasonal allergic rhinitis, prevalin