Features of urine microflora in diabetic patients


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The article is devoted to the problem of contamination of urinary tract by mono- or mixed cultures of microorganisms in patients with diabetes mellitus (DM). 76 patients were examined, including 31 (40.79%) with DM1 and 45 (59.21%) with DM2. Diabetic nephropathy was diagnosed in 31 (40.79%) patients out of a total number of patients. Among all urine samples tested, only 8 (10.53%) were found to be sterile. 86 strains of opportunistic pathogens were isolated from 68 (89.47%) samples of the biomaterial. In DM1 patients, coagulase-negative staphylococci (32.25%) and enterococci (29.03%) were prevalent; in DM2 patients Enterobacteriaceae family representatives dominated (34.55%). The highest susceptibility to nitrofurans (nitrofurantoin) and carbapenems (imipenem, meropenem) was observed for all isolated microorganisms. Nitrofurantoin, imipenem, cefepime and ampicillin can be recommended as the drugs of choice for the treatment of urinary tract infections in diabetic patients.

Толық мәтін

Рұқсат жабық

Авторлар туралы

A. Chikanova

FSBEI HE “Irkutsk State Medical University" of RMH

L. Khamnuyeva

FSBEI HE “Irkutsk State Medical University" of RMH; SBHCI “Irkutsk Order of the Badge of Honour Regional Clinical Hospital"

Email: hamnueval@mail.ru
MD, Head of the Department of Endocrinology and Clinical Pharmacology

O. Karnoukhova

FSBEI HE “Irkutsk State Medical University" of RMH

N. Sudakova

FSBEI HE “Irkutsk State Medical University" of RMH

N. Tokareva

SBHCI “Irkutsk Order of the Badge of Honour Regional Clinical Hospital"

Әдебиет тізімі

  1. Анисимова Н.Е., Аристархов В.Г К вопросу о своевременном выявлении острого пиелонефрита у больных сахарным диабетом. Российский медико-биологический вестник им. Акад. И.П. Павлова. 2012;4:99-101.
  2. ВОЗ - Всемирная организация здравоохранения [Электронный ресурс] // http://www.who. int/mediacentre/factsheets/fs312/ru/ (дата обращения 12.10.2017).
  3. Каюков И.Г, Есаян А.М. Пациент с коморбидным мочевых путей у пациентов с сахарным диабетом. Терапия. 2017;2(12):52-68.
  4. Хопельман А, Гирлингс С. Инфекции мочевыводящих путей при сахарном диабете. Клиническая микробная и антимикробная химиотерапия. 2000;2:40-5.
  5. Шамхалова М.Ш., Чугунова Л.А. Инфекция мочевыводящих путей у больных сахарным диабетом: диагностика, профилактика, лечение. Сахарный диабет. 2001;3:24-30.
  6. Aswani S.M., Chandrashekar U., Shivashankara K., Pruthvi B. Clinical profile of urinary tract infections in diabetics and nondiabetics. Australas. Med. J. 2014;7(1):29-34.
  7. Grabe M., Bartoletti R., Bjerklund Johansen T.E.,et al. Guidelines on urological infections. 2015 (http://uroweb.org/wp-content/ uploads/19-Urological-infections_LR2.pdf).
  8. Renko M., Tapanainen P., Tossavainen P, Pokka T, Uhari M. Meta-analysis of the significance of asymptomatic bacteriuria in diabetes. Diabetes Care. 2011;34(1):230-35.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

© Bionika Media, 2017