Features of urine microflora in diabetic patients


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Abstract

The article is devoted to the problem of contamination of urinary tract by mono- or mixed cultures of microorganisms in patients with diabetes mellitus (DM). 76 patients were examined, including 31 (40.79%) with DM1 and 45 (59.21%) with DM2. Diabetic nephropathy was diagnosed in 31 (40.79%) patients out of a total number of patients. Among all urine samples tested, only 8 (10.53%) were found to be sterile. 86 strains of opportunistic pathogens were isolated from 68 (89.47%) samples of the biomaterial. In DM1 patients, coagulase-negative staphylococci (32.25%) and enterococci (29.03%) were prevalent; in DM2 patients Enterobacteriaceae family representatives dominated (34.55%). The highest susceptibility to nitrofurans (nitrofurantoin) and carbapenems (imipenem, meropenem) was observed for all isolated microorganisms. Nitrofurantoin, imipenem, cefepime and ampicillin can be recommended as the drugs of choice for the treatment of urinary tract infections in diabetic patients.

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About the authors

A. Yu Chikanova

FSBEI HE “Irkutsk State Medical University" of RMH

L. Yu Khamnuyeva

FSBEI HE “Irkutsk State Medical University" of RMH; SBHCI “Irkutsk Order of the Badge of Honour Regional Clinical Hospital"

Email: hamnueval@mail.ru
MD, Head of the Department of Endocrinology and Clinical Pharmacology

O. G Karnoukhova

FSBEI HE “Irkutsk State Medical University" of RMH

N. S Sudakova

FSBEI HE “Irkutsk State Medical University" of RMH

N. P Tokareva

SBHCI “Irkutsk Order of the Badge of Honour Regional Clinical Hospital"

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