CLINICAL FEATURES OF THE ANTIOXIDANT SYSTEM AND SOME CANDIDATE GENES POLYMORPHISMS IN THE PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
- Авторлар: Lapinsky I.V1, Avalueva E.B1, Bakulin I.G1, Dadali V.A1, Topanova A.A2, Skazyvaeva E.V1, Pushkina A.V1
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Мекемелер:
- North-Western State Medical University n.a. I.I. Mechnikov
- Almazov National Medical Research Centre
- Шығарылым: № 9 (2018)
- Беттер: 48-55
- Бөлім: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/295601
- DOI: https://doi.org/10.18565/pharmateca.2018.9.48-55
- ID: 295601
Дәйексөз келтіру
Аннотация
Толық мәтін
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Авторлар туралы
I. Lapinsky
North-Western State Medical University n.a. I.I. Mechnikov
Email: lapinsky85@yandex.ru
Assistant at the Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietology
E. Avalueva
North-Western State Medical University n.a. I.I. Mechnikov
I. Bakulin
North-Western State Medical University n.a. I.I. Mechnikov
V. Dadali
North-Western State Medical University n.a. I.I. Mechnikov
A. Topanova
Almazov National Medical Research Centre
E. Skazyvaeva
North-Western State Medical University n.a. I.I. Mechnikov
A. Pushkina
North-Western State Medical University n.a. I.I. Mechnikov
Әдебиет тізімі
- Bellentani S., Scaglioni F., Marino M., Bedogni G. Epidemiology of non-alcoholic fatty liver disease. Dig. Dis. 2010;28:155-61. doi: 10.1159/000282080.
- Rolo A.P., Teodoro J.S., Palmeira C.M. Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. Free Radic. Biol. Med. 2012;52:59-69. doi: 10.1016/j.freeradbiomed.2011.10.003.
- Бакулин И.Г., Сандлер Ю.Г., Кейян В.А. и др. Оценка стеатоза печени с помощью неинвазивного метода: миф или реальность? Доктор.Ру. 2015;12(113):57-64. [Bakulin I.G., Sandler Yu.G., Kejyan КА., et al. Evaluation of liver steatosis by non-invasive method: myth or reality? Doktor.Ru. 2015;12(113):57-64. (In Russ.)].
- Fassio E., Alvarez E., Dominguez N., et al. Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies. Hepatology. 2004;40:820-26. doi: 10.1002/hep.20410.
- Charlton M.R., Burns J.M., Pedersen R.A., et al. Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States. Gastroenterology. 2011;141:1249-53. doi: 10.1053/j.gastro.2011.06.061.
- Бакулин И.Г., Шаликиани Н.В. Патогенез алкогольного заболевания печени: современные представления. Доктор.Ру 2015;12(113):7-14. [Bakulin LG., Shalikiani N.V Pathogenesis of alcoholic liver disease: modern concepts. Doktor.Ru. 2015;12(113):7-14. (In Russ.)].
- Belfort R., Harrison S.A., Brown K., et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis N. Engl. J. Med. 2006;355:2297-307. DOI: 10.1056/ NEJMoa060326.
- Betrapally N.S., Gillevet P.M., Bajaj J.S. Changes in the Intestinal Microbiome and Alcoholic and Nonalcoholic Liver Diseases: Causes or Effects? Gastroenterology. 2016;150(8):1745-55. Doi: 10.1053/j. gastro.2016.02.073.
- Caldwell S.H., Swerdlow R.H., Khan E.M., et al. Mitochondrial abnormalities in non-alcoholic steatohepatitis. Hepatol. 1999;31:430-34.
- Chatham J., Chacko V.P., Arnold C., et al. Alterations in H. liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA. 1999;282: 1659-64.
- Serviddio G., Bellanti F., Tamborra R., et al. Alterations of hepatic ATP homeostasis and respiratory chain during development of non-alcoholic steatohepatitis in a rodent model. Eur J. Clin. Invest. 2008;38:245-52. doi: 10.1111/j.1365-2362.2008.01936.x.
- Betrapally N.S., Gillevet P.M., Bajaj J.S. Changes in the Intestinal Microbiome and Alcoholic and Nonalcoholic Liver Diseases: Causes or Effects? Gastroenterology. 2016;150(8):1745-55. Doi: 10.1053/j. gastro.2016.02.073.
- Timlin M.T., Parks E.J. Temporal pattern of de novo lipogenesis in the postprandial state in healthy men. Am. J. Clin. Nutr. 2005;81:35-42. Doi: 10.1093/ ajcn/81.1.35.
- Donnelly K.L., Smith C.I., Schwarzenberg S.J., et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.Am. J. Clin. Invest. 2005;115:1343-51. doi: 10.1172/JCI23621.
- De C.D., Pauwels M., Van den Branden C. Alterations of peroxisomes in steatosis of the human liver: a quantitative study. Hepatology. 1995;22:744-52.
- Sunny N.E., Parks E.J., Browning J.D., Burgess S.C. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. Cell. Metab. 2011;14:804-10. Doi:
- W16/j.cmet.2011.11.004.
- Wei X., Wang D., Topczewski F., Pagliassotti M.J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am. J. Physiol. Endocrinol. Metab. 2006;291:275-81. Doi: 10.1152/ ajpendo.00644.2005.
- Muriel P. Role of free radicals in liver diseases. Hepatol. Int. 2009;3:526-36.
- Houstis N.,. Rosen E.D., Lander E.S. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature. 2006;440:944-8. Doi:: 10.1038/ nature04634.
- Arrese M., Karpen S.J. Nuclear receptors, inflammation, and liver disease: insights for cholestatic and fatty liver diseases. Clin. Pharmacol. Ther. 2010;87:473 - 78.
- Wagner M., Zollner G., Trauner M. Nuclear receptors in liver disease. Hepatology. 2011;53:1023-34. doi: 10.1002/hep.24148.
- Spiegelman B.M. PPARy: adipogenic regulator and thiazolidinedione receptor. Diabetes. 1998; 4:507-14.
- Бондарева Э.А., Андреев Р.С., Якушкин А.В. и др. Полиморфизм генов разобщающих белков семейства UCP у футболистов: в поисках функциональной роли. Физиология человека. 2016;42(6):70-80.
- Schrauwen P., Hoeks J., Hesselink M.K. Putative function and physiological relevance of the mitochondrial uncoupling protein-3: involvement in fatty acid metabolism? Prog. Lipid. Res. 2006;45(1):17-41. doi: 10.1016/j.plipres.2005.11.001.
- Boudina S., Graham T.E. Mitochondrial function/ dysfunction in white adipose tissue. Exp. Physiol. 2014;99(9):1168-78. Doi: 10.1113/ expphysiol.2014.081414.
- Farhangi M., Mohseni F., Farajnia S., Jafarabadi M. Major components of metabolic syndrome and nutritional intakes in different genotype of UCP2 -866G/A gene polymorphisms in patients with NAFLD. Transl. Med. 2016;14:177. Doi: 10.1186/ s12967-016-0936-3.
- Brondani L.A., Assmann T.S., Duarte G.C., et al. The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus. Arq. Bras. Endocrinol. Metabol. 2012;56:215.
- Wang C., Gong J., Wu H. Development of gene polymorphisms in meditators of nonalcoholic fatty liver disease. Biomed. Rep. 2017;7(2):95-104. doi: 10.3892/br.2017.926.
- Комелина Н.П., Амерханов З.Г. Разобщающие белки UCP2 и UCP3 митохондрий печени и мышц суслика spermophilus undulates в отличие от UCP1 бурого жира не способны к неспецифическому транспорту пирувата. Биологические мембраны. Журнал мембранной и клеточной биологии. 2013;30(5-6): 412-21.
- Leclercq A. Antioxidant defence mechanisms: new players in the pathogenesis of non-alcoholic steatohepatitis? Clin. Sci.2004;106:235-37. doi: 10.1042/CS20030368.
- Leiers B., Kampkötter A., Grevelding C.G., et al. A stress-responsive glutathione S-transferase confers resistance to oxidative stress in Caenorhabditis elegans. Radic. Biol. Med. 2003;34(11):1405-15. doi: 10.1016/S0891-5849(03)00102-3
- Fuchs M., Sanyal A.J. Lipotoxicity in NASH. J. Hepatol. 2012;56:291-3. doi: 10.1016/j.jhep.2011.05.019.
- Videla L.A., Rodrigo R., Orellana M., et al. Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients. Clin. Sci. 2004;106:261-68. doi: 10.1042/CS20030285.
- Carmiel-Haggai M., Cederbaum A.I., Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J. 2005;19:136-38. doi: 10.1096/fj.04-2291fje.
- Perlemuter G., Davit-Spraul A., Cosson C., et al. Increase in liver antioxidant enzyme activities in nonalcoholic fatty liver disease. Liver Int. 2005;25:946-
- doi: 10.1111/j.1478-3231.2005.01126.x.
- Kohjima M., Enjoji M., Higuchi N., et al. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int. J. Mol. Med. 2007;20:351-58.
- Li L. Yang X. The Essential Element Manganese, Oxidative Stress, and Metabolic Diseases: Links and Interactions. Oxid. Med. Cell. Longev. 2018:7580707. doi: 10.1155/2018/7580707.
- Borrelli A., Bonelli P., Tuccillo FM., et al. Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver diseaseto hepatocarcinoma: Current and innovative therapeutic approaches. Redox Biol. 2018;15:467-79. Doi: 10.1016/j. redox.2018.01.009.
- Yates M.S., Tran Q.T., Dolan P.M., et al. Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice. Carcinogenesis. 2009;30:1024-31. doi: 10.1093/carcin/bgp100.
- Променашева Т.Е. Роль оксидативного стресса и системы глутатиона в патогенезе неалкогольной жировой болезни печени. Бюллетень ВСНЦ СО РАМН. 2014;5(99):80-3.
- Hashemi M., Eskandari-Nasab E., Fazaeli A., et al. Association of genetic polimorphisms of glutathione-S-transferase genes (GSTT1, GSTM1 and GSTP1) and susceptibility to nonalcoholic fatty liver disease in Zahedan. DNA Cell. Biol. 2012;31(5):7-672. doi: 10.2217/bmm.12.61.
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