Discoid lupus erythematosus

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Дәйексөз келтіру

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Аннотация

The article presents data on discoid lupus erythematosus (DLE), characterized by a staged development of erythematous rash, follicular hyperkeratosis and cicatricial atrophy. Disease manifestations are associated with significant discomfort due to frequent occurrence on the face, scalp, ears; appearance of scarring. Factors that increase the likelihood of developing DLE include skin phototype I, drug intolerance, prolonged sun exposure, exposure to cold and wind, a history of chronic infection, and female gender. Ultraviolet radiation, dysregulation of the function of cytotoxic T-lymphocytes, dendritic cells and natural killers are pathogenetic components of the disease. Currently, the treatment of patients is associated with certain difficulties and the likelihood of relapse after discontinuation of drugs or after repeated exposure to trigger factors, which significantly worsens their quality of life.

Толық мәтін

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Авторлар туралы

Luiza Yusupova

Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education

Email: yuluizadoc@hotmail.com
Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology Kazan, Russia

Z. Garayeva

Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education

Kazan, Russia

E. Yunusova

Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education

Kazan, Russia

G. Mavlyutova

Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education

Kazan, Russia

L. Fatkhutdinova

Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education

Kazan, Russia

Әдебиет тізімі

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