Discoid lupus erythematosus
- 作者: Yusupova L.A.1, Garayeva Z.S.1, Yunusova E.I1, Mavlyutova G.I1, Fatkhutdinova L.I1
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隶属关系:
- Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education
- 期: 卷 29, 编号 14 (2022)
- 页面: 10-14
- 栏目: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/321152
- DOI: https://doi.org/10.18565/pharmateca.2022.14.10-14
- ID: 321152
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详细
The article presents data on discoid lupus erythematosus (DLE), characterized by a staged development of erythematous rash, follicular hyperkeratosis and cicatricial atrophy. Disease manifestations are associated with significant discomfort due to frequent occurrence on the face, scalp, ears; appearance of scarring. Factors that increase the likelihood of developing DLE include skin phototype I, drug intolerance, prolonged sun exposure, exposure to cold and wind, a history of chronic infection, and female gender. Ultraviolet radiation, dysregulation of the function of cytotoxic T-lymphocytes, dendritic cells and natural killers are pathogenetic components of the disease. Currently, the treatment of patients is associated with certain difficulties and the likelihood of relapse after discontinuation of drugs or after repeated exposure to trigger factors, which significantly worsens their quality of life.
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作者简介
Luiza Yusupova
Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional Education
Email: yuluizadoc@hotmail.com
Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Cosmetology Kazan, Russia
Z. Garayeva
Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional EducationKazan, Russia
E. Yunusova
Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional EducationKazan, Russia
G. Mavlyutova
Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional EducationKazan, Russia
L. Fatkhutdinova
Kazan State Medical Academy - Branch Campus of the Russian Medical Academy of Continuous Professional EducationKazan, Russia
参考
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