Patient-oriented choice of therapy for inflammatory bowel diseases: a clinical case

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The presented clinical case demonstrates the difficulties in choosing biological therapy for induction and maintenance of remission of Crohn’s disease (CD) and the need for a patient-oriented approach taking into account the patient’s profile and clinical situation. TOne of the effective drugs with a high safety profile, including elderly patients, low immunogenicity, which remains effective in the 2nd and further line of biological therapy, is an anti-cytokine drug, a monoclonal antibody against the p40 subunits of IL-12 and IL-23 ustekinumab.

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作者简介

I. Bakulin

North-Western State Medical University named after I.I. Mechnikov

Email: Mariya.Zhuravleva@szgmu.ru
ORCID iD: 0000-0002-6151-2021

Dr. Sci. (Med.), Professor, Head of the Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietetics named after S.M. Ryss

俄罗斯联邦, St. Petersburg

Maria Zhuravleva

North-Western State Medical University named after I.I. Mechnikov

编辑信件的主要联系方式.
Email: Mariya.Zhuravleva@szgmu.ru
ORCID iD: 0000-0003-4838-5707

Cand. Sci. (Med.), Associate Professor, Associate Professor at the Department of Propaedeutics of Internal Medicine, Gastroenterology and Dietetics named after S.M. Ryss

俄罗斯联邦, St. Petersburg

M. Bereznitskaya

North-Western State Medical University named after I.I. Mechnikov

Email: Mariya.Zhuravleva@szgmu.ru
ORCID iD: 0009-0007-1407-1378

Resident in the specialty «Gastroenterology», Department of Propaedeutics of Internal Diseases, Gastroenterology and Dietetics named after S.M. Ryss

俄罗斯联邦, St. Petersburg

E. Gutman

Leningrad Regional Clinical Hospital

Email: Mariya.Zhuravleva@szgmu.ru
ORCID iD: 0009-0007-3025-2195

Head of the Gastroenterology Department

俄罗斯联邦, St. Petersburg

T. Egorova

Leningrad Regional Clinical Hospital

Email: Mariya.Zhuravleva@szgmu.ru
ORCID iD: 0009-0001-4114-4882

Gastroenterologist, Gastroenterology Department

俄罗斯联邦, St. Petersburg

参考

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2. Рис. Эндофото колоноскопии (ноябрь 2022 г.) пациента Ш. (предоставлено врачом-эндоскопистом отделения эндоскопии больницы им. Петра Великого Голубевой К.В.) A - сливные эрозии слизистой оболочки нисходящей ободочной кишки, покрытые фибрином; Б - зона стриктуры сигмовидной кишки; В - сливные эрозии, спонтанная кровоточивость слизистой оболочки сигмовидной кишки.

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