CHRONIC CEREBRAL ISCHEMIA: PATHOGENETIC MECHANISMS AND PRINCIPLES OF TREATMENT


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Cerebrovascular diseases are one of the major problems of modern neuroscience. The most common disease - chronic cerebral ischemia (CCI), resulting in vascular dementia in some cases. The CCI most often occurs in elderly patients with burdened somatic history. Development of CCI is based on structural changes of the vascular wall, increased blood viscosity, increased platelet aggregation and impaired deformability of erythrocytes. Drugs with complex mechanism of action, which provide the normalization of cerebral hemodynamics and improvement of microcirculation, are widely used in the complex treatment of patients with CCI. One of these drugs, Vasonit (international name - pentoxifylline) is an effective and safe treatment for CCI.

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