Klinicheskie maski glyutenchuvstvitel'noy tseliakii
- Autores: Parfenov A.I1
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Afiliações:
- Edição: Nº 13 (2012)
- Páginas: 26-31
- Seção: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/279735
- ID: 279735
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Resumo
A variety of clinical variants of celiac disease (CD) is related to the different degrees of toxic effects of gluten on the small intestine mucosa (SIM) in gliadin-hypersensitive genetically susceptible individuals with HLA DQ2 or DQ8 alleles, autoimmune disorders and selective malabsorption of iron, calcium, vitamins and other nutrients. Some patients with gluten sensitivity have CD symptoms, but they have no specific changes of SIM, and compliance with a gluten-free diet leads to the disappearance of clinical symptoms. In the absence of gluten allergy, these cases are corresponded to the term “gluten intolerance unrelated to celiac disease". The article presents data on the progress in diagnosis and treatment of CD.
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Bibliografia
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