Rol' ranney antiagregantnoy terapii pri ostrom koronarnom sindrome bez pod\"ema segmenta ST na dogospital'nom etape

Unstable angina and myocardial infarction without ST-segment elevation are the most common forms of acute coronary syndrome (ACS). At the pre-hospital stage of emergency medical services (EMS), optimizing of antiplatelet therapy in this actual pathology is pathogeneti-cally justified and necessary. The aim of study was to evaluate the effectiveness of early administration of acetylsalicylic acid (ASA) and magnesium hydroxide (Cardiomagnyl) in patients with ACS without ST-segment elevation at the pre-hospital stage. A retrospective analysis of 3858 patients with ACS without ST elevation who sought emergency medical care in 2008-2010 was performed. With the increasing frequency of aspirin use in ACS without ST-segment elevation at the pre-hospital stage from 2008 to 2010 (from 46.4 to 56.7 and 93.8%, respectively), the incidence of myocardial infarction in the hospital has decreased from 134 (10%) to 111 (8.9%) and 86 (6.8%) cases, respectively; in addition, hospital mortality in this disease has reduced from 11.7 to 11.5% and 9.6% in the dynamics by years. Due to the effectiveness of early use of ASA, this drug should be administered in patients with complaints of chest pain during reception of call by dispatcher of ambulance care.

acute coronary syndrome without ST elevation, pre-hospital stage, emergency medical care, antiplatelet therapy, antiplatelets, acetylsalicylic acid