Роль тиотропия бромида в базисной терапии хронической обструктивной болезни легких


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Аннотация

Современный уровень развития клинической медицины дает возможность эффективно воздействовать на течение хронической обструктивной болезни легких (ХОБЛ). Особое место среди лекарственных средств, используемых в терапии стабильного периода ХОБЛ, занимают длительнодействующие бронходилататоры (ДДБД), в частности тиотропия бромид, который относится к базисным препаратам длительной поддерживающей терапии ХОБЛ. Тиотропий улучшает функциональные легочные показатели, симптомы, физическую работоспособность, качество жизни больных ХОБЛ, уменьшает число обострений заболевания.

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Об авторах

С. Н Авдеев

НИИ пульмонологии ФМБА России

Email: serg_avdeev@list.ru
д.м.н., проф., рук. клинического отдела

Список литературы

  1. Global Initiative for Chronic Obstructive Lung Diseas (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO workshop report. The 2009 report is available on www.goldcopd. com
  2. Buist AS, McBurnie MA, Vollmer WM, et al. International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. Lancet 2007;370:741 -50.
  3. Чучалин А.Г., Овчаренко С.И, Лещенко И.В, Белевский А.С. Определение, классификация и диагностика ХОБЛ. В кн.: Клинические рекомендации. Хроническая обструктивная болезнь легких / Под ред. А.Г. Чучалина. М., 2007. С. 8-22.
  4. Celli BR, MacNee W. ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004;23:932-46.
  5. Panning CA, DeBisschop M. Tiotropium: an inhaled, long-acting anticholinergic drug for chronic obstructive pulmonary disease. Pharmacotherapy 2003;23:183-89.
  6. Tashkin DP. Long-acting anticholinergic use in chronic obstructive pulmonary disease: efficacy and safety. Curr Opin Pulm Med 2010;16:97-105.
  7. Donohue JF, van Noord JA, Bateman ED, et al. A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol. Chest 2002;122:47-55.
  8. Celli B, Wallack RZ, Wang S, et al. Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes. Chest 2003; 124:1743-48.
  9. Cazzola M, Matera MG. Emerging inhaled bronchodilators: an update. Eur Respir J 2009;34:757-69.
  10. Bauwens O, Ninane V, Van de Maele B, et al. 24-hour bronchodilator efficacy of single doses indacaterol in subjects with COPD: comparison with placebo and formoterol. Curr Med Res Opin 2009;25:463-70.
  11. Beier J, Beeh KM, Brookman L, et al. Bronchodilator effects of indacaterol and formoterol in patients with COPD. Pulm Pharmacol Ther 2009;22(6):492-96.
  12. Fogarty C, Worth H, Hebert J, et al. Sustained 24-h bronchodilation with indacaterol once-daily in COPD: a 26-week efficacy and safety study. Am J Respir Crit Care Med 2009; 179: A4547.
  13. Magnussen H, Paggiaro P, Jack D, et al. Bronchodilatador treatment with indacaterol once-daily vs formoterol twice - daily in COPD: a 52-week study. Am J Respir Crit Care Med 2009;179:A6184.
  14. Nonikov V, Verkindre C, Jack D, et al. Indacaterol once-daily reduces days of poor control in COPD over 52 weeks of treatment. Am J Respir Crit Care Med 2009;179 A6190.
  15. Magnussen H, Paggiaro P, Jack D, et al. Indacaterol once-daily improves health-related quality of life in COPD patients: a 52-week study versus placebo and formoterol. Eur Respir J 2009;53s:P2019.
  16. Buhl R, Pieters W, Jack D, et al. Indacaterol once-daily improves dyspnoea and BODE index in COPD patients: a 52- week study versus twice-daily formoterol. Eur Respir J 2009;53s:P2026.
  17. Buhl R, Pieters W, Jack D, et al. Indacaterol once-daily reduces COPD exacerbations over 52 weeks of treatment. Am J Respir Crit Care Med 2009;179:A6185.
  18. Worth H, Kleerup E, Iqbal A, et al. Safety and tolerability of indacaterol once-daily in COPD patients versus placebo and tiotropium: a 26-week study. Eur Respir J 2009;53s:P2030.
  19. Chung F, Kornmann O, Jack D, et al. Safety and tolerability of indacaterol over 52 weeks of treatment in COPD. Eur Respir J 2009;53s:E4359.
  20. Fletcher CM. Elmes PC, Wood CH. The significance of respiratory symptoms and the diagnosis of chromic bronchitis in a working population. BMJ 1959;1:257-66.
  21. Kohansal R, Martinez-Camblor P, Agust A, et al. The Natural History of Chronic Airflow Obstruction Revisited: An Analysis of the Framingham Offspring Cohort Am J Respir Crit Care Med 2009;180:3-10.
  22. Decramer M, Celli B, Tashkin DP, et al. Clinical trial design considerations in assessing long-term functional impacts of tiotropium in COPD: the Uplift trial. COPD 2004;1 303-12.
  23. Scanlon PD, Connett JE, Waller LA, et al. Smoking cessation and lung function in mild-to-moderate chronic obstructive pulmonary disease: the Lung Health Study. Am J Respir Crit Care Med 2000;161 381-90.
  24. Anthonisen NR, Skeans MA,Wise RA, et al. The effects of a smoking cessation intervention on 14.5-year mortality: a randomized clinical trial. Ann Intern Med 2005;142: 233-39.
  25. Tashkin DP, Celli B, Senn S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008;359:1543-54.
  26. Vincken W, van Noord JA, Greefhorst APM, et al. Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium. Eur Respir J 2002; 19:209-16.
  27. Anzueto A, Tashkin D, Menjoge S, Kesten S. One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium. Pulm Pharmacol Ther 2005;18:75-81.
  28. Pauwels RA, Lofdahl CG, Laitinen LA, et al. Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking. N Engl J Med 1999;340:1948-53.
  29. Vestbo J, Sorensen T, Lange P, et al. Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 1999;353: 1819-23.
  30. The Lung Health Study Research Group. Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease. N Engl J Med 2000;343:1902-909.
  31. Burge PS, Calverley PMA, Jones PW, et al. Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial. BMJ 2000;320:1297-303.
  32. Decramer M, Rutten-van Molken M, Dekhuijzen PN, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomized placebo-controlled trial. Lancet 2005;365:1552-60.
  33. Calverley P, Pauwels R, Vestbo J, et al. Combined salmeterol and fluticasone in the treatment of COPD: a randomised controlled trial. Lancet 2003;361(9356):449-56.
  34. Decramer M, Celli B, Kesten S, et al., for the UPLIFT investigators. Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecied subgroup analysis of a randomised controlled trial. Lancet 2009;374:1171-78.
  35. Troosters T, Celli B, Lystig T, et al. Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial. Eur Respir J 2010;36:65-73.
  36. Morice AH, Celli B, Kesten S, et al. COPD in young patients: A pre-specified analysis of the four-year trial of tiotropium (UPLIFT). Respir Med 2010;104:1659-67.
  37. Murray CJL, Lopez AD. Mortality by cause for eight regions of the world: global burden of disease study. Lancet 1997;349: 1269-76.
  38. Mannino DM, Homa DM, Akinbami LJ, et al. Chronic obstructive pulmonary disease surveillance - United States, 1971-2000. MMWR Surveill Summ 2002;51:1-16.
  39. World Health Organization. Global initiative for chronic obstructive lung disease. Geneva (Switzerland): World Health Organization; 2002.
  40. Medical Research Council Working Party. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet 1981;i:681-86.
  41. Nocturnal Oxygen Therapy Trial Group: Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Ann Intern Med 1980;93:391 -98.
  42. Anthonisen NR, Skeans MA,Wise RA, et al. The effects of a smoking cessation intervention on 14,5-year mortality: a randomized clinical trial. Ann Intern Med 2005;142:233-39.
  43. National Emphysema Treatment Trial Research Group. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N Engl J Med 2003;348:2059-73.
  44. Lightowler JV, Wedzicha JA, Elliott MW, Ram FS. Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. BMJ 2003;326:185-89.
  45. Salpeter SR, Buckley NS, Salpeter EE. Metaanalysis: Anticholinergics, but not b-agonists, Reduce Severe Exacerbations and Respiratory Mortality in COPD. J Gen Intern Med 2006;21:1011-19.
  46. De Luise C, Lanes SF, Jacobsen J, et al. Cardiovascular and respiratory hospitalizations and mortality among users of tiotropium in Denmark. Eur J Epidemiol 2007; 22:267-72.
  47. Hansell AL, Walk JA, Soriano JB. What do chronic obstructive pulmonary disease patients die from? A multiple cause coding analysis. Eur Respir J 2003;22:809-14.
  48. Camilli AE, Robbins DR, Lebowitz MD. Death certificate reporting of confirmed airways obstructive disease. Am J Epidemiol 1991; 133:795-800.
  49. Engstrom G, Wollmer P, Hedblad B, et al. Occurrence and prognostic significance of ventricular arrhythmia is related to pulmonary function: a study from "men born in 1914", Malmo, Sweden. Circulation 2001;103:3086-91.
  50. Huiart L, Ernst P, Suissa S. Cardiovascular morbidity and mortality in COPD. Chest 2005; 128:2640-46.
  51. Viegas CA, Ferrer A, Montserrat JM. Ventilation-perfusion response after fenoterol in hypoxemic patients with stable COPD. Chest 1996;110:71-7.
  52. Singh S, Loke YK, Furberg CD. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease. A systematic review and metaanalysis. JAMA 2008;300:1439-50.
  53. Celli B, Decramer M, Leimer I, et al. Cardiovascular safety of tiotropium in patients with COPD. Chest 2010;137;20-30.
  54. Reilly JJ. COPD and Declining FEV1 -Time to Divide and Conquer? N Engl J Med 2008;359:1616-18.
  55. Burrows B, Fletcher CM, Heard BE, et al. The emphysematous and bronchial types of chronic airways obstruction. A clinicopathological study of patients in London and Chicago. Lancet 1966;87: 830-35.
  56. Garcia-Aymerich J, Agusti А, Barber JA, et al. Phenotypic Heterogeneity of Chronic Obstructive Pulmonary Disease. Arch Bronconeumol 2009;45:133-42.
  57. Han MK, Agusti A, Calverley PM, et al. COPD phenotypes: The future of COPD. Am J Respir Crit Care Med 2010; 182:598-604.
  58. Lee J-H, Lee YK, Kim E-K, et al. Responses to inhaled long-acting beta-agonist and corticosteroid according to COPD subtype. Respir Med 2010;104:542-49.
  59. Gelb AF, Taylor CF, Cassino C, et al. Tiotropium induced bronchodilation and protection from dynamic hyperinflation is independent of extent of emphysema in COPD. Pulm Pharmacol Ther 2009; 22:237-42.
  60. Tashkin DP, Celli B, Kesten S, et al. Long-term efficacy of tiotropium in relation to smoking status in the UPLIFT trial. Eur Respir J 2010; 35:287-94.
  61. Tashkin DP, Celli B, Kesten S, et al. Effect of tiotropium in men and women with COPD: Results of the 4-year UPLIFT trial. Respir Med 2010;104:1495-504.

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