ADIPONEKTIN, LEPTIN I DRUGIE METABOLIChESKIE POKAZATELI U BOL'NYKh GIPOTIREOZOM
- Autores: Verbovaya N.I1, Kapralova I.Y.1, Verbovoy A.F1
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Afiliações:
- Edição: Nº 10 (2014)
- Páginas: 67-69
- Seção: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/287061
- ID: 287061
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Resumo
The article presents the results of evaluation of the relationship of adiponectin, leptin, and hormonal-metabolic parameters based on the survey of 93 women with hypothyroidism. In patients with hypothyroidism, insulin resistance and compensatory hyperinsulinemia were identified. They also have pronounced atherogenic dyslipidemia, which was expressed by elevated levels of total cholesterol, triglycerides, low density lipoprotein cholesterol, and atherogenic index, and decreased level of high density lipoprotein cholesterol. In women with hypothyroidism, concentration of leptin was increased and adiponectin levels were reduced. It is obvious that changes of these adipokines play a role in the development of atherogenic dyslipidemia.
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Bibliografia
- Аметов А.С. Избранные лекции по эндокринологии. М., 2009. 496 с.
- Вербовой А.Ф. Гипотиреоз. Терапевт. 2011; 12: 22-6.
- Зефирова Г.С. Заболевания щитовидной железы. М., 1999. 215 с.
- Фадеев В.В., Мельниченко Г.А. Гипотиреоз: руководство для врачей. М., 2002. 216 с.
- Соломонова Е., Вербовой А. Жировая ткань и адипокины. LAP. Lambert Academic Publishing, 2012. 115 с.
- Петунина Н.А., Альтшулер Н.Э. Сравнительный анализ уровней адипонектина, лептина, резистина, показателей липидного обмена и инсулинорезистентности при субклиническом гипотиреозе в зависимости от наличия/ отсутствия заместительной терапии левотироксином. Эндокринология. Новости. Мнения. Обучение. 2013; 2: 27-31.
- Ройтберг Г.Е. Метаболический синдром. М., 2007. 224 с.
- Wolk R., Berger P., Lennon R.J., et al. Plasma leptin and prognosis in patients with established coronary atherosclerosis. J. Am. Coll. Cardiol. 2004; 44: 1819-24.