ROL' MAKROLIDOV V LEChENII PATOLOGII LOR-ORGANOV


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Resumo

Modern macrolides firmly won their place in the treatment of inflammatory diseases of the respiratory tract due to the high antibacterial activity against Gram-positive cocci, Haemophilus pertussis, Corynebacterium diphtheriae, Moraxella, Legionella, Campylobacter, Listeria, Spirochetes, Chlamydia, Mycoplasma, Ureaplasma, anaerobes and some protozoa. The combination of additional effects that are not associated with an antimicrobial effect, opens up new prospects in the application of macrolides. In this review, characteristics of roxithromycin presented in more detail; this drug has been used successfully in the clinical practice due to the optimal parameters of pharmacokinetics and good tolerability.

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